Metoprolol (By mouth)

Introduction

Metoprolol (met-oh-PROE-lol)

Treats high blood pressure and angina (chest pain), and lowers the risk of repeated heart attacks. It is also used to treat heart failure. This medicine is a beta-blocker.

Brand Name(s)

There may be other brand names for this medicine.

Toprol XL, Lopressor, Metoprolol Tartrate, Toprol-XL

When This Medicine Should Not Be Used

You should not use this medicine if you have had an allergic reaction to metoprolol or any beta-blocker medicine (such as atenolol, propranolol, Corgard®, Inderal®, Lopressor®, or Tenormin®). Do not use this medicine if you have blood circulation problems, lung problems (such as asthma, bronchitis, or emphysema), or certain heart problems. Talk with your doctor about what these heart problems are.

How to Use This Medicine

Tablet, Long Acting Tablet

  • Your doctor will tell you how much of this medicine to use and how often. Your dose may need to be changed several times in order to find out what works best for you. Do not use more medicine or use it more often than your doctor tells you to.
  • Take this medicine with a meal or just after you eat. You may break the extended-release tablet in two pieces, but swallow the two pieces whole and do not crush or chew them.
  • Carefully follow your doctor's instructions about any special diet.

If a dose is missed:

  • If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine after you have finished your treatment. You will also need to throw away old medicine after the expiration date has passed.
  • Keep all medicine away from children and never share your medicine with anyone.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using clonidine (Catapres®), digoxin (Lanoxin®), reserpine, medicine to treat depression (such as bupropion, fluoxetine, paroxetine, Paxil®, Prozac®, or Wellbutrin®), an MAO inhibitor (such as isocarboxazid, phenelzine, selegiline, tranylcypromine, Eldepryl®, Marplan®, Nardil®, or Parnate®), medicine to treat mental illness (such as thioridazine, Mellaril®), medicine for heart rhythm problems (such as propafenone, quinidine, or Rhythmol®), medicine to treat HIV or AIDS (such as ritonavir, Norvir®), an allergy medicine (such as diphenhydramine, Benadryl®), medicine to treat malaria (such as hydroxychloroquine, quinidine, or Plaquenil® Sulfate), medicine to treat a fungus infection (such as terbinafine, Lamisil®), or a stomach medicine (such as cimetidine, Tagamet®).
  • Make sure your doctor knows if you are also using certain blood pressure medicines (such as diltiazem, verapamil, Cardizem®, Calan®, Isoptin®, or Verelan®), or a diuretic or "water pill" (such as furosemide, hydrochlorothiazide [HCTZ], torsemide, Demadex®, or Lasix®).

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have liver disease, blood vessel problems, angina (chest pain), low blood pressure, diabetes, an overactive thyroid, or an adrenal gland tumor called a pheochromocytoma.
  • Do not stop using this medicine suddenly without asking your doctor, or you may develop life-threatening heart problems. You may need to slowly decrease your dose before stopping it completely.
  • Call your doctor right away if you have rapid weight gain, shortness of breath, or troubled breathing. These may be signs of a serious heart problem.
  • Make sure any doctor or dentist who treats you knows that you are using this medicine. You may need to stop using this medicine several days before having surgery or medical tests.
  • This medicine may raise or lower your blood sugar, or it may cover up symptoms of very low blood sugar (hypoglycemia). If you have diabetes, report any changes in your blood sugar to your doctor.
  • This medicine may make you dizzy or drowsy. Avoid driving, using machines, or doing anything else that could be dangerous if you are dizzy or not alert.
  • Dizziness, lightheadedness, or even fainting may occur when you get up suddenly from a lying or sitting position. Getting up slowly may help lessen this problem. Also, lying down for a while may relieve the dizziness or lightheadedness.
  • If you stop using this medicine, your blood pressure may go up. High blood pressure usually has no symptoms. Even if you feel well, do not stop using the medicine without talking to your doctor.
  • Your doctor will need to check your progress at regular visits while you are using this medicine. Be sure to keep all appointments.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
  • Chest pain.
  • Fever, chills, cough, sore throat, and body aches.
  • Lightheadedness or fainting.
  • Rapid weight gain.
  • Shortness of breath, cold sweats, and bluish-colored skin.
  • Skin rash or itching.
  • Slow, fast, pounding, or uneven heartbeat.
  • Swelling in your hands, ankles, or feet.
  • Unusual bleeding or bruising.
  • Wheezing or trouble with breathing.

If you notice these less serious side effects, talk with your doctor:

  • Blurred vision.
  • Cold hands and feet.
  • Diarrhea, constipation, nausea, vomiting, heartburn, or upset stomach.
  • Dry mouth.
  • Feeling dizzy, drowsy, confused, depressed, or tired.
  • Headache.
  • Hearing loss.
  • Memory problems, nightmares, or unusual dreams.
  • Muscle or joint pain.
  • Problems with sex.
  • Sleepiness or trouble sleeping.
  • Stuffy or runny nose.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Review Date: 2011-02-04 Reviewed By: Keywords: ,
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