Diltiazem (By mouth)

Introduction

Diltiazem (dil-TYE-a-zem)

Treats high blood pressure and chest pain (angina). This medicine is a calcium channel blocker.

Brand Name(s)

There may be other brand names for this medicine.

Cartia XT, Taztia XT, Cardizem CD, Diltia XT, Tiazac, Dilt-XR, Dilt-CD, Dilacor XR, Diltzac, Cardizem SR, Cardizem, Cardizem LA

When This Medicine Should Not Be Used

You should not use this medicine if you have had an allergic reaction to diltiazem or similar medicines (such as verapamil, Adalat®, Calan®, Lotrel®, Plendil®, or Procardia®), or if you have very low blood pressure or certain heart problems. Talk with your doctor about what these heart problems are.

How to Use This Medicine

Long Acting Capsule, 12 Hour Capsule, 24 Hour Capsule, Tablet, Long Acting Tablet

  • Your doctor will tell you how much of this medicine to use and how often. Your dose may need to be changed several times in order to find out what works best for you. Do not use more medicine or use it more often than your doctor tells you to.
  • It is best to take this medicine on an empty stomach.
  • Swallow the long-acting capsule, 24-hour capsule, 12-hour capsule, or long-acting tablet whole. Do not crush, break, or chew it.

If a dose is missed:

  • If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine after you have finished your treatment. You will also need to throw away old medicine after the expiration date has passed.
  • Keep all medicine away from children and never share your medicine with anyone.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • There are many other medicines that can interact with diltiazem. Make sure your doctor knows about ALL other medicines you are using. This includes over-the-counter medicines that can increase your blood pressure (such as diet pills, cold and allergy medicines, or asthma medicines).
  • Make sure your doctor knows if you are also using buspirone (Buspar®), carbamazepine (Tegretol®), cimetidine (Tagamet®), cyclosporine (Gengraf®, Neoral®, Sandimmune®), digoxin (Lanoxin®), lovastatin (Mevacor®), quinidine (Quinora®), rifampin (Rifadin®, Rimactane®), other medicine to lower blood pressure (such as atenolol, metoprolol, propranolol, timolol, Inderal®, or Toprol®), or medicine for sleeping (such as midazolam, triazolam, Halcion®, or Versed®).

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart rhythm problems, congestive heart failure, or stomach problems.
  • This medicine may make you dizzy or drowsy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.
  • Your doctor will need to check your progress at regular visits while you are using this medicine. Be sure to keep all appointments.
  • If you stop using this medicine, your blood pressure may go up. High blood pressure usually has no symptoms. Do not stop using this medicine suddenly without asking your doctor. You may need to slowly decrease your dose before stopping it completely.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
  • Blistering, peeling, or red skin rash.
  • Chest pain (may be related to your disease and not a side effect).
  • Fast, slow, uneven, or pounding heartbeat.
  • Swelling in your hands, ankles, or feet.
  • Unusual tiredness or weakness.
  • Wheezing or trouble breathing.

If you notice these less serious side effects, talk with your doctor:

  • Mild skin rash.
  • Runny or stuffy nose.
  • Stomach discomfort.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Review Date: 2011-02-04 Reviewed By: Keywords: ,
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