Betamethasone/clotrimazole (On the skin)


Betamethasone Dipropionate (bay-ta-METH-a-sone dye-PROE-pee-oh-nate), Clotrimazole (kloe-TRIM-a-zole)
Treats athlete's foot, ringworm, and other fungus infections. Betamethasone is a steroid. Clotrimazole is an antifungal agent.

Brand Name(s)

There may be other brand names for this medicine.


When This Medicine Should Not Be Used

You should not use this medicine if you have had an allergic reaction to clotrimazole or similar drugs, such as butoconazole (Gynazole®), miconazole (Monistat®), econazole (Spectazole®), or ketoconazole (Nizoral®). Also avoid using the medicine if you have had an allergic reaction to betamethasone or medicines such as hydrocortisone (Hytone®), fluocinonide (Lidex®), or triamcinolone (Aristocort®). This medicine should not be used to treat diaper rash.

How to Use This Medicine

Cream, Lotion
  • Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to.
  • This medicine is for use on the skin only. Do not get it in your eyes, nose, mouth, or in or around the vagina. Do not use it on skin areas that have cuts or scrapes. If it does get on these areas, rinse it off right away.
  • Wash your hands with soap and water before and after using this medicine.
  • Apply a thin layer to the affected area. Rub it in gently.
  • Shake the bottle of lotion well just before using.
  • Do not cover the treated area with a bandage unless your doctor has told you to.Wear loose-fitting clothes if you are using this medicine to treat an infection in the groin area.
  • Keep using this medicine for the full treatment time, even if you feel better after the first few doses. Your infection may not clear up if you stop using the medicine too soon.
If a dose is missed:
  • If you miss a dose or forget to use your medicine, apply it as soon as you can. If it is almost time for your next dose, wait until then to apply the medicine and skip the missed dose. Do not apply extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Store the lotion bottle upright, not laying on its side.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of the used medicine container and any leftover medicine after you have finished your treatment. You will also need to throw away old medicine after the expiration date has passed.
  • Keep all medicine away from children and never share your medicine with anyone.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
  • Before using this medicine, make sure your doctor knows if you are using other medicines on your skin, or if you are using any steroid medicines.
  • Do not use cosmetics or other skin care products on the treated skin areas.

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have an active infection of the skin, such as herpes or chickenpox.
  • Tell your doctor if you have diabetes. This medicine may raise the levels of sugar in your blood or urine.
  • Do not give this medicine to your child unless your doctor tells you to. Children may be more likely to have serious side effects from this medicine.
  • Do not use this medicine for a skin problem that has not been checked by your doctor.
  • If your symptoms do not improve after 1 or 2 weeks of treatment with this medicine, or if they get worse, check with your doctor. This medicine should not be used for a long time.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
  • Severe itching, burning, or skin irritation.
  • Signs of infection such as redness, swelling, drainage, or pus.
If you notice these less serious side effects, talk with your doctor:
  • Irritation, burning, redness, peeling, or blistering of the skin.
  • Mild, temporary stinging.
  • Numbness or tingling at the site of application.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
Review Date: 2011-02-04 Reviewed By: Keywords: ,
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