Treats ulcerative proctitis, a bowel disease.
There may be other brand names for this medicine.
Canasa, Rowasa, sfRowasa
When This Medicine Should Not Be Used
Do not use this medicine if you have had an allergic reaction to mesalamine or salicylates (such as aspirin). Do not use the rectal suppository if you are allergic to saturated vegetable fat such as shortening.
How to Use This Medicine
- Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to.
- Use the enema at bedtime, unless your doctor tells you otherwise. Shake the bottle and then remove the cap.
- Wash your hands with soap and water before and after using this medicine.
- Lie on your left side with your left leg straight or slightly bent, and your right knee bent upward. Insert the applicator tip into your rectum about an inch. Gently squeeze the bottom of the bottle to release the enema.
- Remove the bottle and throw it away.
- You may need to hold the liquid in your rectum for several minutes or hours. This may be difficult or feel uncomfortable. It should become easier to do as you continue to use the medicine.
- Never take rectal suppositories by mouth.
- Use this medicine at bedtime, unless your doctor tells you otherwise.
- Before inserting a suppository, go to the bathroom and empty your bladder and, if possible, have a bowel movement.
- This medicine will stain any surface it touches (such as clothing, bedsheets, floors, and countertops). To protect your clothing, consider wearing a sanitary napkin or adult undergarment such as Depend®. Protect your sheets by placing a waterproof pad on your bed. These pads, often called Chux® pads or underpads, are available from a medical supply store.
- Wash your hands with soap and water before and after using this medicine. Remove the foil or wrapper from the suppository before inserting it.
- Do not keep the suppository in your hand too long or it will begin to melt. To make the suppository easier to insert, you may use a lubricating gel such as K-Y® Jelly, but do not use petroleum jelly (Vaseline®).
- Lie on your left side with your left leg straight or slightly bent, and your right knee bent upward. Gently push the pointed end of the suppository into the rectum about 1 inch.
- The medicine needs to remain in your body for 1 to 3 hours or longer, depending on your doctor's advice. Try not to use the bathroom for at least that length of time after inserting the suppository.
- This medicine comes with patient instructions. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions.
If a dose is missed:
- If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.
How to Store and Dispose of This Medicine
- You may store the suppositories in the refrigerator, but do not freeze them.Store the enema at room temperature. Keep away from heat, moisture, or direct light.
- Ask your pharmacist, doctor, or health caregiver about the best way to dispose of the used medicine applicator(s), containers, and any leftover medicine after you have finished your treatment. You will also need to throw away old medicine after the expiration date has passed.
- Keep all medicine away from children and never share your medicine with anyone.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Make sure your doctor knows if you are also taking mesalamine by mouth (Asacol®, Pentasa®), azathioprine (Imuran®), mercaptopurine (Purinethol®), or an NSAID pain or arthritis medicine (such as aspirin, diclofenac, ibuprofen, naproxen, Advil®, Aleve®, Celebrex®, Voltaren®).
Warnings While Using This Medicine
- Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, or a history of heart disease (such as myocarditis or pericarditis).
- Tell your doctor if you have had an allergic reaction to sulfasalazine (Azulfidine®).
- Check with your doctor right away if you have stomach pain, bloody diarrhea, and cramps, especially if you also have fever, headache, or a rash. These may be symptoms of an acute intolerance syndrome that your doctor will need to treat.
- Your doctor will need to check your blood or urine at regular visits while you are using this medicine. Be sure to keep all appointments.
Possible Side Effects While Using This Medicine
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Bloody diarrhea, severe cramping, stomach pain, possibly with fever, headache, rash
- Change in how much or how often you urinate
- Chest pain, trouble breathing
- Fast, slow, or pounding heartbeat
If you notice these less serious side effects, talk with your doctor:
- Mild headache or dizziness
- Mild stomach discomfort, nausea, diarrhea, gas