Introduction

Desmopressin (des-moe-PRES-in)

Treats bleeding disorders such as hemophilia A and von Willebrand's disease. Also treats diabetes insipidus, a condition that causes the body to lose too much fluid and become dehydrated.

Brand Name(s)

There may be other brand names for this medicine.

When This Medicine Should Not Be Used

You should not use this medicine if you have had an allergic reaction to desmopressin, or if you have moderate to severe kidney disease.

How to Use This Medicine

Injectable

• Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin, or into a vein.
• A nurse or other trained health professional will give you this medicine. Sometimes you, a family member, or a friend can be taught to give your medicine.
• Your doctor may give you instructions for drinking a certain amount of liquid each day while you are using this medicine. Follow these instructions carefully.

If a dose is missed:

• This medicine needs to be given on a fixed schedule. If you miss a dose or forget to use your medicine, call your doctor or pharmacist for instructions.

How to Store and Dispose of This Medicine

• If you store this medicine at home, keep it in the refrigerator. Do not freeze.
• Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine, containers, and other supplies. You will also need to throw away old medicine after the expiration date has passed.
• Throw away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.
• Keep all medicine away from children and never share your medicine with anyone.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• There are some drugs that can interact with desmopressin. Make sure your doctor knows about all other medicines you are using.

Warnings While Using This Medicine

• Make sure your doctor knows if you are pregnant or breastfeeding, or if you have heart problems, high blood pressure, kidney disease, or problems with fluid balance such as cystic fibrosis.
• Your doctor will need to check your progress at regular visits while you are using this medicine. Be sure to keep all appointments.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
• Crushing chest pain that may radiate to the jaw or arms.
• Fast, pounding, or irregular heartbeat.
• Rapid weight gain.
• Seizures or tremors.

If you notice these less serious side effects, talk with your doctor:

• Flushing (redness) in the face.
• Headache.
• Mild stomach pain, nausea, or vomiting.
• Pain, swelling, or burning sensation on injection site.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088