Phytonadione (Injection)


Phytonadione (fye-toe-na-DYE-one)
A form of vitamin K used as a supplement to prevent bleeding disorders.

Brand Name(s)

There may be other brand names for this medicine.


When This Medicine Should Not Be Used

You should not use this medicine if you have ever had an allergic reaction to vitamin K or if you are in the last few weeks of pregnancy.

How to Use This Medicine

  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin, into a muscle, or into a vein.
  • This medicine can sometimes be added to total parenteral nutrition (TPN) solutions. Make sure you understand how to open the ampule (the tube the medicine comes in) and add the medicine to your TPN liquid. Your doctor or caregiver will tell you how to use the medicine.
  • A nurse or other trained health professional will give you this medicine.
  • You may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.
  • If you are getting the IV medicine, check the bag to make sure there are no leaks. Make sure the liquid in the bag is clear.
If a dose is missed:
  • This medicine needs to be given on a regular schedule. Take the missed dose as soon as you remember. Then go back to your usual dosing schedule.
  • If you miss more than one dose, call your doctor for instructions.

How to Store and Dispose of This Medicine

  • If you see specks in the IV liquid, you should not use it.
  • If you have your treatments at home, you should be given a special container for the used needles. Keep it where children or pets cannot reach it.
  • Keep the medicine at room temperature and away from direct light.
  • Keep all medicine out of the reach of children.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
  • Be sure your doctor knows if you are taking a blood thinner (such as Coumadin®), aspirin, or an antibiotic before you take this medicine.

Warnings While Using This Medicine

  • If you are pregnant or breastfeeding, talk to your doctor before taking this medicine.
  • Do not eat any more green, leafy vegetables (foods high in vitamin K) than usual.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:
  • Rash or hives
  • Wheezing or trouble breathing
  • Dizziness, fast or irregular heartbeat
If you notice these less serious side effects, talk with your doctor:
  • Strange taste in your mouth
  • Pain, swelling, or tenderness where the shot was given

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
Review Date: 2011-02-04 Reviewed By: Keywords: ,
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