Carvedilol (By mouth)

Introduction

Carvedilol (kar-VE-dil-ol)

Treats high blood pressure and congestive heart failure (CHF). Also reduces the risk of death from a heart attack. This medicine is a beta-blocker.

Brand Name(s)

There may be other brand names for this medicine.

Coreg, Coreg CR

When This Medicine Should Not Be Used

You should not use this medicine if you have had an allergic reaction to carvedilol. Do not use this medicine if you have asthma, severe liver disease, or certain heart problems. Talk with your doctor about what these heart problems are.

How to Use This Medicine

Long Acting Capsule, Tablet

  • Your doctor will tell you how much of this medicine to use and how often. Your dose may need to be changed several times in order to find out what works best for you. Do not use more medicine or use it more often than your doctor tells you to.
  • It is best to take this medicine with food or milk. If you are using the extended-release capsule, take it in the morning.
  • Swallow the extended-release capsule whole. Do not crush, break, or chew it.
  • If you cannot swallow the extended-release capsule, you may open it and pour the medicine into a small amount of soft food such as pudding, yogurt, or applesauce. Stir this mixture well and swallow it without chewing.
  • This medicine comes with patient instructions. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions.

If a dose is missed:

  • If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine after you have finished your treatment. You will also need to throw away old medicine after the expiration date has passed.
  • Keep all medicine away from children and never share your medicine with anyone.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using any other heart medicine such as amiodarone (Cordarone®), clonidine (Catapres®), diltiazem (Cardizem®), propafenone (Rythmol®), quinidine, or verapamil (Calan®). Tell your doctor if you are also using cyclosporine (Gengraf®, Neoral®, Sandimmune®), digoxin (Digitek®, Lanoxin®), fluconazole (Diflucan®), fluoxetine (Prozac®), paroxetine (Paxil®), reserpine (Serpalan®), rifampin (Rifadin®), or a stomach medicine (such as cimetidine, Tagamet®).
  • Make sure your doctor knows if you are also using an MAO inhibitor (MAOI) such as Eldepryl®, Marplan®, Nardil®, or Parnate®. Tell your doctor if you are also using a diabetes medicine such as glyburide, insulin, metformin, Actos®, Glucophage®, Glucotrol®, or Glucovance®.

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, bradycardia (slow heartbeat), coronary artery disease, circulation problems, diabetes, edema (fluid retention or body swelling), heart or blood vessel problems, low blood pressure, lung or other breathing problems (such as bronchitis or emphysema), an overactive thyroid, pheochromocytoma (adrenal gland tumor), or if you are having frequent chest pains. Tell your doctor if you have severe allergic reactions in the past or if you have a scheduled surgery.
  • Do not stop using this medicine suddenly without asking your doctor. You may need to slowly decrease your dose before stopping it completely.
  • If you stop using this medicine, your blood pressure may go up. High blood pressure usually has no symptoms. Even if you feel well, do not stop using the medicine without asking your doctor.
  • This medicine may raise or lower your blood sugar, or it may cover up symptoms of very low blood sugar (hypoglycemia). If you have diabetes, report any changes in your blood sugar to your doctor.
  • This medicine may make you dizzy or drowsy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert. You may also feel lightheaded when getting up from a lying or sitting position, so stand up slowly.
  • If you are wearing contact lens, this medicine may cause your eyes to form tears less than they do normally. Check with your doctor if you have dry eyes.
  • Make sure any doctor or dentist who treats you knows that you are using this medicine. You may need to stop using this medicine several days before having surgery or medical tests.
  • Your doctor will need to check your progress at regular visits while you are using this medicine. Be sure to keep all appointments.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
  • Change in how much or how often you urinate.
  • Chest pain (may be related to your disease and not a side effect).
  • Confusion, weakness, irregular heartbeat, shortness of breath, or numbness or tingling in your hands, feet, or lips.
  • Fainting or severe dizziness.
  • Fast, slow, or uneven heartbeat.
  • Sudden weight gain.
  • Swelling of your feet or ankles.
  • Unusual bleeding or bruising.
  • Wheezing or trouble breathing.

If you notice these less serious side effects, talk with your doctor:

  • Diarrhea.
  • Dry eyes.
  • Trouble having sex.
  • Unusual tiredness or weakness.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Review Date: 2011-02-04 Reviewed By: Keywords: ,
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