Trovafloxacin (By mouth)

Introduction

Trovafloxacin (troe-va-FLOX-a-sin)

Treats infections that are caused by bacteria. This medicine is a fluoroquinolone antibiotic. The marketing and distribution of trovafloxacin (and alatrofloxacin) have been discontinued.

Brand Name(s)

There may be other brand names for this medicine.

When This Medicine Should Not Be Used

You should not use this medicine if you have ever had an allergic reaction to trovafloxacin or to similar medicines such as ciprofloxacin (Cipro®), enoxacin (Penetrex®), gatifloxacin (Tequin?), levofloxacin (Levaquin®), lomefloxacin (Maxaquin?), moxifloxacin (Avelox®), norfloxacin (Noroxin®), or ofloxacin (Floxin®). This medicine should not be given to children.

How to Use This Medicine

Tablet

  • Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to.
  • Keep using this medicine for the full treatment time, even if you feel better after the first few doses. Your infection may not clear up if you stop using the medicine too soon.
  • You may take your medicine with food.
  • Drink extra fluids so you will pass more urine while you are using this medicine. This will keep your kidneys working well and help prevent kidney problems.

If a dose is missed:

  • If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine after you have finished your treatment. You will also need to throw away old medicine after the expiration date has passed.
  • Keep all medicine away from children and never share your medicine with anyone.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using blood thinners (Coumadin®), omeprazole (Prilosec®), or theophylline.
  • If you are also using antacids, multivitamins (with calcium, iron, or zinc), sucralfate (Carafate®), or didanosine (Videx®) powder or chewable/buffered tablets, take these medicines at least 2 hours before or 2 hours after you take trovafloxacin.
  • Avoid caffeine (coffee, soda, chocolate) while you are using this medicine.

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have a history of heart disease, heart rhythm problems, hypokalemia (low blood potassium), stroke, or seizure disorder (such as epilepsy).
  • This medicine may make your skin more sensitive to sunlight. Use a sunscreen when you are outdoors. Avoid sunlamps and tanning beds.
  • Call your doctor if you have pain, swelling, or tearing of a tendon, such as in the back of your knee or ankle, in your shoulder or elbow, or in your hand or wrist. You may need to stop taking the medicine.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
  • Chest pain.
  • Dark colored urine, pale stools, yellow eyes or skin.
  • Diarrhea.
  • Fast or slow heartbeat.
  • Lightheadedness or fainting.
  • Seizures.
  • Sudden and severe stomach pain, nausea, vomiting, fever, lightheadedness.
  • Unusual bleeding or bruising, skin rash, redness, blistering, or peeling.

If you notice these less serious side effects, talk with your doctor:

  • Dizziness, nervousness, anxiety, confusion, or agitation.
  • Headache or tiredness.
  • Muscle or joint pain.
  • Nausea, vomiting, stomach pain, or constipation.
  • Nightmares or trouble sleeping.
  • Sores or white patches in your mouth or throat.
  • Vaginal itching or discharge.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Review Date: 2011-02-04 Reviewed By: Keywords: ,
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