Celecoxib (By mouth)

Introduction

Celecoxib (sel-e-KOX-ib)

Treats pain, including pain caused by arthritis (osteoarthritis, rheumatoid arthritis, or juvenile rheumatoid arthritis) in children and adults, ankylosing spondylitis, or menstrual cramps. Also reduces colorectal polyps in people with familial adenomatous polyposis (FAP). This is a non-steroidal anti-inflammatory medicine (NSAID).

Brand Name(s)

There may be other brand names for this medicine.

Celebrex

When This Medicine Should Not Be Used

You should not use this medicine if you have had an allergic reaction (including asthma) to celecoxib, a sulfa drug, or NSAID medicines such as aspirin, diclofenac, ibuprofen, naproxen, Advil®, Aleve®, Ecotrin®, Motrin®, or Voltaren®. Do not use this medicine right before or right after having coronary artery bypass graft (CABG), a type of heart surgery.

How to Use This Medicine

Capsule

  • Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to.
  • It is best to take this medicine with food or milk, so it does not upset your stomach.
  • This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions. Ask your pharmacist for the Medication Guide if you do not have one. Your doctor might ask you to sign some forms to show that you understand this information.
  • Use this medicine for the shortest time possible and in the smallest dose possible. This will help lower the risk of side effects.
  • If you cannot swallow the capsule, you may open it and pour the medicine into a teaspoon of applesauce. Stir the mixture well and swallow right away. Drink enough water after to make sure you swallow any excess medicine in mouth.

If a dose is missed:

  • If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Any medicine that has been mixed with applesauce may be stored in a refrigerator and used within 6 hours.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
  • Keep all medicine away from children and never share your medicine with anyone.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using aspirin, lithium, a blood thinner such as warfarin (Coumadin®), a steroid such as cortisone, dexamethasone, hydrocortisone, methylprednisolone, prednisolone, prednisone, Orapred®, or a diuretic ("water pill") such as furosemide, hydrochlorothiazide (HCTZ), torsemide, Demadex®, Lasix®.
  • Do not use any other NSAID medicine unless your doctor tells you to. Some other names are aspirin, diclofenac, ibuprofen, naproxen, Advil®, Aleve®, Ecotrin®, Motrin®, or Voltaren®.
  • Make sure your doctor knows if you are also using fluconazole (Diflucan®), lithium (Eskalith®), or medicine to lower blood pressure, such as enalapril, lisinopril, Accupril®, Lotrel®, Zestril®.
  • Do not drink alcohol while you are using this medicine.

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breastfeeding. You should not use this medicine during the later part of pregnancy unless your doctor tells you to.
  • Make sure your doctor knows if you have high blood pressure, congestive heart failure (CHF), or other heart or circulation problems. Also tell your doctor if you have liver disease, kidney disease, asthma, or a bleeding problem.
  • This medicine may raise your risk of having a heart attack or stroke. This is more likely in people who already have heart disease. People who use this medicine for a long time might also have a higher risk.
  • This medicine might cause bleeding in your stomach or intestines. This is more likely if you have had a stomach ulcer in the past, if you smoke or drink alcohol regularly, if you are over 60 years old, if you are in poor health, or if you are using certain other medicines (a steroid or a blood thinner).
  • If you are using this medicine to treat Familial Adenomatous Polyposis (FAP), you still need to continue all other medical care as instructed by your doctor. This medicine will not cure FAP.
  • Make sure any doctor or dentist who treats you knows that you are using this medicine.
  • Your doctor will need to check your blood or urine at regular visits while you are using this medicine. Be sure to keep all appointments.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
  • Blistering, peeling, red skin rash.
  • Bloody or black, tarry stools.
  • Change in how much or how often you urinate.
  • Chest pain, shortness of breath, or coughing up blood.
  • Fever, chills, sore throat.
  • Nausea, vomiting, loss of appetite, pain in your upper stomach.
  • Numbness or weakness in your arm or leg, or on one side of your body.
  • Pain in your lower leg (calf).
  • Rapid weight gain
  • Severe stomach pain.
  • Shortness of breath, cold sweat, and bluish-colored skin.
  • Sudden or severe headache, problems with vision, speech, or walking.
  • Swelling in your hands, ankles, or feet.
  • Unusual tiredness or weakness, pale skin.
  • Vomiting blood or material that looks like coffee grounds.
  • Yellowing of your skin or the whites of your eyes.

If you notice these less serious side effects, talk with your doctor:

  • Mild nausea, stomach pain, diarrhea, gas.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Review Date: 2011-02-04 Reviewed By: Keywords: ,
Adam Data Copyright The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only--they do not constitute endorsements of those other sites. © 1997- 2010 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

For information 410.787.4000

© 2013 UM Baltimore Washington Medical Center.  All rights reserved.

301 Hospital Drive, Glen Burnie, MD 21061 | 410-787-4000 | TTY 410-787-4498