Amphotericin B cholesteryl sulfate complex (Injection)


Amphotericin B Cholesteryl Sulfate Complex (am-foe-TER-i-sin B koe-les-TEER-il SUL-fate KOM-plex)
Treats infections caused by a fungus. Belongs to a class of drugs called antifungals.

Brand Name(s)

There may be other brand names for this medicine.


When This Medicine Should Not Be Used

You should not use this medicine if you have ever had an allergic reaction to amphotericin B.

How to Use This Medicine

  • Your doctor will prescribe your exact dose and tell you how often it should be given.
  • An intravenous (in-tra-VEEN-us) or IV injection is given through a tube put in one of your veins, usually in your arm, wrist, hand, or sometimes in your chest.
  • A nurse or other caregiver trained to give injections will give your treatment.
  • Never share your medicine with anyone.
If a dose is missed:
  • This medicine needs to be given on a regular schedule.
  • Use the missed dose as soon as you remember.
  • If you miss more than one dose, call your doctor for instructions.

How to Store and Dispose of This Medicine

  • If you have your treatments at home, you should be given a special container for the used needles. Keep it where children or pets cannot reach it.
  • Store this medicine in a refrigerator. Do not freeze.
  • Keep all medicine away from children.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
  • Make sure your doctor knows if you are also using any antibiotic or other antifungal medicine (such as Ancobon®, Nizoral®, or Monistat®), cancer medicines, a corticosteroid (such as prednisone or cortisone), corticotropin (ACTH), cyclosporin, digoxin (Lanoxin®), muscle relaxants, pentamidine, or tacrolimus.

Warnings While Using This Medicine

  • If you are pregnant or breastfeeding, talk to your doctor before using this medicine.
  • Make sure your doctor knows if you have kidney disease.
  • Your doctor may want to test your blood while you are receiving this medicine. Be sure to keep all appointments.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:
  • Fainting
  • Fever and chills
  • Severe nausea and vomiting
  • Swelling, pain, or redness near where the IV needle is given
  • Trouble breathing
If you notice these less serious side effects, talk with your doctor:
  • Fast heartbeat
  • Headache
  • Mild nausea or upset stomach

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
Review Date: 2011-02-04 Reviewed By: Keywords: ,
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