Linezolid (Injection)

Introduction

Linezolid (lin-AYZ-oh-lid)

Treats bacterial infections and certain types of skin infections or pneumonia. This medicine is an antibiotic.

Brand Name(s)

There may be other brand names for this medicine.

Zyvox

When This Medicine Should Not Be Used

You should not use this medicine if you have had an allergic reaction to linezolid.

How to Use This Medicine

Injectable

  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given through a needle placed in one of your veins.
  • A nurse or other trained health professional will give you this medicine. It may also be given by a home health caregiver.
  • Keep using this medicine for the full treatment time, even if you feel better after the first few doses. Your infection may not clear up if you stop using the medicine too soon.

How to Store and Dispose of This Medicine

  • If you store this medicine at home, keep it at room temperature, away from heat and direct light. Keep the medicine bag in the wrapping until you are ready to use it. Do not freeze.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine, containers, and other supplies. You will also need to throw away old medicine after the expiration date has passed.
  • Throw away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.
  • Keep all medicine away from children and never share your medicine with anyone.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using a cold medicine, or a decongestant such as pseudoephedrine. Tell your doctor if you are using medicine for depression, anxiety, or panic disorder. These may include citalopram, fluoxetine, paroxetine, sertraline, amitriptyline, doxepin, nortriptyline, Celexa®, Effexor®, Lexapro?, Paxil®, Prozac®, Sarafem®, Zoloft®, Elavil®, Pamelor®, or Sinequan®.
  • Make sure your doctor knows if you are also using an MAO inhibitor (MAOI) such as Eldepryl®, Marplan®, Nardil®, or Parnate®. Avoid foods or drinks that contain tyramine. This includes aged cheeses, dried meats, sauerkraut, soy sauce, tap beers, or red wines.

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breast feeding. Your doctor will need to know if you have bone marrow problems, high blood pressure, kidney disease, or if you are on dialysis. Tell your doctor if you have any other infections that you are treating with other antibiotics. Tell your doctor if you have pheochromocytoma, carcinoid syndrome, or untreated hyperthyroidism (overactive thyroid).
  • If you have severe diarrhea, ask your doctor before taking any medicine to stop the diarrhea.
  • Your doctor will need to check your blood at regular visits while you are using this medicine. Be sure to keep all appointments.
  • If your symptoms do not improve or if they get worse, call your doctor.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
  • Diarrhea that may contain blood.
  • Extreme weakness, tiredness, or confusion.
  • High fever.
  • Lightheadedness or fainting.
  • Numbness, tingling, or burning pain in your hands, arms, legs, or feet.
  • Rapid breathing, or severe nausea and vomiting.
  • Unusual bleeding or bruising.

If you notice these less serious side effects, talk with your doctor:

  • Headache.
  • Mild nausea, diarrhea, or vomiting.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Review Date: 2011-02-04 Reviewed By: Keywords: ,
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