Pantoprazole (Injection)

Introduction

Pantoprazole (pan-TOE-pra-zole)

Treats gastroesophageal reflux disease (GERD) in people who have had damage to the lining of the esophagus. Also treats high levels of acid in the stomach that is caused by a tumor (such as in Zollinger-Ellison syndrome). This medicine is a proton pump inhibitor (PPI).

Brand Name(s)

There may be other brand names for this medicine.

Protonix, Novaplus Protonix

When This Medicine Should Not Be Used

You should not use this medicine if you have had an allergic reaction to pantoprazole.

How to Use This Medicine

Injectable

  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given through a needle placed in one of your veins.
  • A nurse or other trained health professional will give you this medicine.
  • Your doctor will give you a few doses of this medicine until your condition improves, and then switch you to an oral medicine that works the same way. If you have any concerns about this, talk to your doctor.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using ampicillin (Omnipen®), atazanavir (Reyataz®), ketoconazole (Nizoral®), iron supplements, or a blood thinner (such as warfarin, Coumadin®).

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have liver problems or bone problems (such as osteoporosis). Tell your doctor if you have problems with a lack of zinc (a mineral) in your body.
  • This medicine may cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you have a rash; itching; hoarseness; trouble breathing; trouble swallowing; or any swelling of your hands, face, or mouth after you receive the medicine.
  • Check with your doctor right away if you notice any of these side effects at the injection site: changes in skin color, pain, tenderness, or swelling of the foot or leg.
  • This medicine may increase your risk of having fractures of the hip, wrist, and spine. This is more likely if you are 50 years of age and older, if you receive high doses of this medicine, or use it for one year or more.
  • Do not stop using this medicine suddenly without asking your doctor. You may need to slowly decrease your dose before stopping it completely.
  • Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may affect the results of certain medical tests.
  • Your doctor will need to check your progress at regular visits while you are using this medicine. Be sure to keep all appointments.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
  • Blistering, peeling, or red skin rash.
  • Nausea, vomiting, loss of appetite, or pain in your upper stomach.
  • Redness, swelling, or pain where the needle is placed.
  • Swelling of the foot or leg.
  • Unusual tiredness, weakness, or trouble with muscle coordination.
  • Yellowing of your skin or the whites of your eyes.

If you notice these less serious side effects, talk with your doctor:

  • Diarrhea, constipation, or stomach pain or upset.
  • Dizziness or headache.
  • Stuffy or runny nose.
  • Trouble sleeping.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Review Date: 2011-02-04 Reviewed By: Keywords: ,
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