Hepatitis A/hepatitis B vaccine (Injection)


Hepatitis A Vaccine, Inactivated (hep-a-TYE-tis A VAX-een, in-AK-ti-vay-ted), Hepatitis B Vaccine Recombinant (hep-a-TYE-tis B VAX-een re-KOM-bin-ant)
Prevents infection with hepatitis A and hepatitis B in adults (18 years old or older).

Brand Name(s)

There may be other brand names for this medicine.


When This Medicine Should Not Be Used

You should not use this medicine if you have had an allergic reaction to vaccinations for hepatitis A or hepatitis B. You may not be able to receive this vaccine if you are allergic to yeast or neomycin.

How to Use This Medicine

  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot into one of your muscles.
  • A nurse or other trained health professional will give you this medicine.
  • This vaccine is usually given as a series of shots at three different times. If you are following the usual schedule, you will receive the second shot 1 month after the first, and the third shot 6 months later.
If a dose is missed:
  • This medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor or health caregiver for instructions.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
  • Tell your doctor if you are using a blood thinner such as warfarin (Coumadin®). Make sure your doctor knows if you are using medicines that weaken your immune system, such as a steroid or cancer treatment. Some examples of steroids are dexamethasone, prednisolone, prednisone, and Medrol®.

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breast feeding, or if you have a bleeding disorder or problems with your immune system.
  • Tell your doctor if you have ever had a serious reaction to latex, thimerosal, or any type of vaccine.
  • This vaccine will not keep you from getting sick if you have already caught hepatitis A or B. This medicine will not protect you from hepatitis C.
  • Tell your doctor if you have a cold or the flu, especially if you have a fever. You may need to wait until you are well to receive this vaccine.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
  • Blistering, peeling, red skin rash.
  • Fever, chills, sore throat, or vomiting.
  • Unusual bleeding or bruising.
If you notice these less serious side effects, talk with your doctor:
  • Diarrhea or nausea.
  • Headache.
  • Mild redness, swelling, pain, bruising, or itching where the shot was given.
  • Unusual weakness.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
Review Date: 2011-02-04 Reviewed By: Keywords: ,
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