Immune globulin (Injection)

Introduction

Immune Globulin (im-MYOON GLOB-yoo-lin)

Treats problems with your immune system. Helps prevent infections or makes the infection less severe. Treats primary humoral immunodeficiency (an immune system disorder), idiopathic thrombocytopenic purpura (a blood disorder), and chronic inflammatory demyelinating polyneuropathy (a neuromuscular disorder).

Brand Name(s)

There may be other brand names for this medicine.

GamaSTAN S/D, Gamastan S/D, Gammaplex, Gamunex, Gammagard Liquid, Flebogamma 5% DIF, Flebogamma, Flebogamma 10% DIF, Octagam, Flebogamma 5%, Privigen, Panglobulin NF, Carimune NF, Gammagard S/D, Gammagard S/D (IgA<1ug/ml)

When This Medicine Should Not Be Used

You should not receive this medicine if you have had an allergic reaction to human immune globulin, or if you have an immunoglobulin A (IgA) deficiency with antibodies against IgA and a history of hypersensitivity to human immune globulin.

How to Use This Medicine

Injectable

  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot into one of your muscles or through a needle placed in one of your veins.
  • A nurse or other trained health professional will give you this medicine.

If a dose is missed:

  • Call your doctor, pharmacist, or home health caregiver for instructions.

How to Store and Dispose of This Medicine

  • If you store this medicine at home, ask your pharmacist or health caregiver how to store it. Some brands should be stored at room temperature, away from heat and direct light. Some brands must be stored in the refrigerator.
  • Keep all medicine away from children and never share your medicine with anyone.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows what medications you are taking. It is important the he/she is aware of other medications that may affect your kidney.
  • Talk to your doctor before getting any vaccines while you are receiving immune globulin. Some vaccines may not work as well while you are using this medicine.

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have a history of kidney problems, diabetes, hyponatremia (low sodium in the blood), paraproteinemia (paraproteins in the blood), hyperproteinemia (high protein in the blood), a recent serious infection, or recent dehydration (not enough fluid in your body). Tell your doctor if you are allergic to latex or anything else, or if you have problems with your immune system.
  • This medicine may cause fever, chills, nausea, and vomiting, especially if you will be receiving it for the first time or if you have not received it for more than 8 weeks. Check with your doctor or nurse right away if you have any of these symptoms.
  • This medicine is made from donated human blood. Some human blood products have transmitted certain viruses to people who have received them. The risk of getting a virus from medicines made from human blood has been greatly reduced in recent years. This is the result of required testing of human donors for certain viruses, and testing during the making of these medicines. Although the risk is low, talk with your doctor if you have concerns.
  • This medicine may cause a serious type of allergic reaction, including anaphylaxis, which can be life-threatening and requires immediate medical attention. Tell your doctor right away if you have itching, hives, hoarseness, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth after you receive this medicine.
  • Check with your doctor right away if you start to have stiff neck, drowsiness, fever, severe headache, nausea or vomiting, painful eye movements, or sensitivity to light. These could be symptoms of a serious condition called aseptic meningitis syndrome (AMS).
  • This medicine may cause blood clots, especially in patients with history of blood clotting problems, heart disease, atherosclerosis (narrowing of the blood vessels), blood problems, or any circulation problems, and those who stay in bed for a long time because of surgery or illness. Check with your doctor right away if you suddenly have chest pain, shortness of breath, severe headache, leg pain, or problems with vision, speech, or walking.
  • Some patients developed a serious lung problem a few hours after receiving the medicine. Tell your doctor right away if you have start to have any problems with your breathing after you receive the medicine.
  • This medicine may cause bleeding (hemolysis) or hemolytic anemia. Tell your doctor right away if you have stomach or back pain, dark urine, decreased urination, increased heart rate, tiredness, or yellow eyes or skin after you receive the medicine.
  • Check with your doctor right away if you start having red or dark brown urine; lower back or side pain; sudden weight gain; swollen face, arms, or legs; decreased urine output; or any problems with urination after you receive this medicine. These may be symptoms of a serious kidney problem.
  • Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may affect the results of certain medical tests.
  • Your doctor will need to check your blood or urine at regular visits while you are using this medicine. Be sure to keep all appointments.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
  • Blistering, peeling, or red skin rash.
  • Bloody, black, or tarry stools.
  • Chest pain, shortness of breath, or coughing up blood.
  • Confusion, weakness, and muscle twitching.
  • Decrease in how much or how often you urinate.
  • Fast, pounding, or uneven heartbeat.
  • Feeling unusually cold, shivering.
  • Fever, chills, cough, runny or stuffy nose, sore throat, and body aches.
  • Lightheadedness, dizziness, or fainting.
  • Lower back or side pain.
  • Numbness or weakness in your arm or leg or on one side of your body.
  • Pain in your lower leg (calf).
  • Problems with vision, speech, or walking.
  • Rapid weight gain.
  • Red or dark brown urine.
  • Seizures or tremors.
  • Severe diarrhea, nausea, vomiting, or stomach pain.
  • Severe headache, stiff neck, sensitivity to light, or painful eye movement.
  • Swelling in your hands, ankles, or feet.
  • Swollen, painful, or tender lymph glands in the neck, armpit, or groin.
  • Unusual bleeding or bruising.
  • Unusual tiredness or weakness.
  • Yellowing of your skin or the whites of your eyes.

If you notice these less serious side effects, talk with your doctor:

  • Anxiety.
  • Back, hip, or joint pain.
  • Ear pain.
  • Mild headache.
  • Mild skin rash.
  • Muscle or joint pain.
  • Pain or redness where the needle is placed.
  • Warmth or redness in the face, neck, arms, or upper chest.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Review Date: 2011-02-04 Reviewed By: Keywords: ,
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