Cinacalcet (By mouth)

Introduction

Cinacalcet (sin-a-KAL-set)

Lowers the amount of calcium in your blood. You might have too much calcium because of cancer, problems with your parathyroid gland, and other conditions.

Brand Name(s)

There may be other brand names for this medicine.

Sensipar

When This Medicine Should Not Be Used

You should not use this medicine if you have had an allergic reaction to cinacalcet.

How to Use This Medicine

Tablet

  • Your doctor will tell you how much of this medicine to use and how often. Your dose may need to be changed several times in order to find out what works best for you. Do not use more medicine or use it more often than your doctor tells you to.
  • Your doctor will use the results of your blood tests to decide how much medicine you should take. Keep all appointments so you can make sure you are using the right amount of medicine.
  • It is best to take this medicine with food or shortly after a meal.
  • Swallow the tablet whole. Do not crush, chew, or break it.

If a dose is missed:

  • If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine after you have finished your treatment. You will also need to throw away old medicine after the expiration date has passed.
  • Keep all medicine away from children and never share your medicine with anyone.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using erythromycin (Ery-tab®), flecainide (Tambocor®), itraconazole (Sporanox®), ketoconazole (Nizoral®), carvedilol (Coreg®), metoprolol (Toprol®), thioridazine (Mellaril®), vinblastine (Velban®), or medicine for depression (such as amitriptyline, desipramine, nortriptyline, Elavil®, Norpramin®, or Vivactil®).

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have liver disease, bone disease, heart disease, heart failure, heart rhythm problems, low blood pressure, or a history of seizures (such as epilepsy).
  • This medicine may lower the calcium in your blood. If you have any of these symptoms, check with your doctor right away: abdominal or stomach cramps; confusion; convulsions; difficulty with breathing; irregular heartbeats; mood or mental changes; muscle cramps in the hands, arms, feet, legs, or face; numbness and tingling around the mouth, fingertips, or feet; shortness of breath; or tremors.
  • Your doctor will need to check your blood at regular visits while you are using this medicine. Be sure to keep all appointments.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
  • Chest pain.
  • Fast, slow, or uneven heartbeat.
  • Fever, chills, cough, sore throat, and body aches.
  • Joint pain.
  • Lightheadedness, dizziness, or fainting.
  • Numbness or muscle pain, stiffness, cramping, or weakness.
  • Seizures.
  • Shortness of breath, cold sweats, and bluish-colored skin.
  • Swelling in your hands, ankles, or feet.

If you notice these less serious side effects, talk with your doctor:

  • Nausea, vomiting, diarrhea, headache, or loss of appetite.
  • Skin rash.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Review Date: 2011-02-04 Reviewed By: Keywords: ,
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