Diazoxide (By mouth)

Introduction

Diazoxide (dye-az-OX-ide)

Treats low blood sugar (hypoglycemia) caused by certain cancers, surgery, or other conditions.

Brand Name(s)

There may be other brand names for this medicine.

Proglycem

When This Medicine Should Not Be Used

You should not use this medicine if you have had an allergic reaction to diazoxide or similar medicines such as hydrochlorothiazide, Aldactazide®, Diuril®, Dyazide®, Maxzide®, or Zaroxolyn®.

How to Use This Medicine

Capsule, Suspension

  • Your doctor will tell you how much of this medicine to use and how often. Your dose may need to be changed several times in order to find out what works best for you. Do not use more medicine or use it more often than your doctor tells you to.
  • Shake the oral liquid well just before each use.
  • Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.
  • Carefully follow your doctor's instructions about any special diet while you are using this medicine.

If a dose is missed:

  • If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Protect the medicine from light. Do not freeze the oral liquid.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
  • Keep all medicine away from children and never share your medicine with anyone.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using phenytoin (Dilantin®), a blood thinner such as warfarin (Coumadin®), or medicine to lower blood pressure. Some blood pressure medicines are atenolol, hydrochlorothiazide (HCTZ), lisinopril, metoprolol, Accupril®, Cozaar®, Diovan®, Lotrel®, Norvasc®, Prinivil®, Toprol®, and Zestril®.

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breast feeding, or if you have gout, heart disease, congestive heart failure, or kidney disease.
  • While you are using this medicine, you will need to test your urine for sugar (glucose) and ketones. This test can be done in your home. It is very important to check your urine on a regular basis and report any abnormal results to your doctor.
  • Your doctor will need to check your blood at regular visits while you are using this medicine. Be sure to keep all appointments.
  • Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may affect the results of certain medical tests.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
  • Fast, pounding heartbeats.
  • Fever, chills, cough, sore throat, and body aches.
  • Increase in how much or how often you urinate.
  • Lightheadedness or fainting.
  • Rapid weight gain.
  • Shortness of breath, cold sweat, and bluish-colored skin.
  • Swelling in your hands, ankles, or feet.
  • Unusual bleeding, bruising, or weakness.
  • Unusual thirst, fruit-like breath odor.

If you notice these less serious side effects, talk with your doctor:

  • Anxiety, dizziness, trouble sleeping.
  • Headache, blurred vision.
  • Loss of taste.
  • Mild skin rash or itching.
  • Nausea, vomiting, diarrhea, loss of appetite, stomach pain.
  • Unusual hair growth on the face, arms, legs, or back.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Review Date: 2011-02-04 Reviewed By: Keywords: ,
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