Apraclonidine (Into the eye)


Apraclonidine (a-pra-KLON-i-deen)
Treats or prevents the build-up of fluid inside the eye (intraocular pressure) before and after laser eye surgery to treat glaucoma or cataracts.

Brand Name(s)

There may be other brand names for this medicine.


When This Medicine Should Not Be Used

You should not receive this medicine if you have had an allergic reaction to apraclonidine or clonidine (Catapres®). You should not use this medicine if you have used an MAO inhibitor (MAOI) such as Eldepryl®, Marplan®, Nardil®, or Parnate® within the past 14 days.

How to Use This Medicine

  • You will receive this medicine as an eyedrop 1 hour before, and just after your eye surgery. The medicine will be put only in the eye or eyes being treated with surgery.
  • A nurse or other trained health professional will give you this medicine.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breast feeding, or if you have high blood pressure or heart disease.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
  • Eye burning, itching, or discomfort.
  • Feeling very cold or sleepy, with shallow breathing.
  • Lightheadedness or fainting.
  • Redness of the white of your eyes.
  • Slow, pounding, or uneven heartbeat.
If you notice these less serious side effects, talk with your doctor:
  • Blurred vision.
  • Dry mouth, unusual taste in your mouth.
  • Feeling like there is something in your eye.
  • Mild itching of your skin.
  • Redness, swelling, or whitening of your eyelids.
  • Runny or stuffy nose.
  • Stomach pain, diarrhea, vomiting.
  • Sweating of your palms.
  • Trouble sleeping, unusual dreams.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
Review Date: 2011-02-04 Reviewed By: Keywords: ,
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