Daclizumab (Injection)

Introduction

Daclizumab (dak-LIZ-oo-mab)

Used with other medicines to keep your body from rejecting a kidney transplant. This medicine suppresses your immune system. Products containing daclizumab were withdrawn from the U.S. market by Roche on September 2009.

Brand Name(s)

There may be other brand names for this medicine.

When This Medicine Should Not Be Used

You should not use this medicine if you have had an allergic reaction to daclizumab.

How to Use This Medicine

Injectable

  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given through a needle placed in one of your veins.
  • A nurse or other trained health professional will give you this medicine.
  • You will receive a total of five doses of this medicine. Your first dose is given to you right before the transplant. Then you will receive one treatment every 14 days.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have high blood pressure or diabetes. This medicine may raise your blood sugar.
  • This medicine may cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Tell your doctor or nurse right away if you have a skin rash; itching; swelling of the face, tongue, and throat; or trouble with breathing after you get the injection.
  • Your doctor will need to check your blood at regular visits while you are using this medicine. Be sure to keep all appointments.
  • You may be more likely to get infections while using this medicine. Tell your doctor if you have symptoms of an infection, such as fever or chills. Try to stay away from people with colds, flu, or other infections.
  • Using this medicine may cause you to have a higher risk of getting cancer of the lymph system. Talk to your doctor if you have concerns about this risk.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
  • Chest pain or fast heartbeat.
  • Fever, chills, cough, sore throat, and body aches.
  • Pain or problems with urination.
  • Swelling in your hands, ankles, or feet.
  • Unusual bleeding or bruising.

If you notice these less serious side effects, talk with your doctor:

  • Back or muscle pain.
  • Diarrhea, constipation, nausea, vomiting, stomach pain, or upset stomach.
  • Headache or dizziness.
  • Redness, pain, swelling, itching, blistering, or rash where the needle is placed.
  • Shivering, shaking, or trembling.
  • Tiredness or weakness.
  • Trouble sleeping.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Review Date: 2011-02-04 Reviewed By: Keywords: ,
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