Polymyxin B (Injection)


Polymyxin B Sulfate (pol-ee-MIX-in B SUL-fate)
Treats infections caused by certain types of bacteria. This medicine is an antibiotic.

Brand Name(s)

There may be other brand names for this medicine.

Novaplus Polymyxin B

When This Medicine Should Not Be Used

You should not use this medicine if you have had an allergic reaction to polymyxin antibiotics.

How to Use This Medicine

  • A nurse or other trained health professional will give you this medicine.This medicine is given as a shot into a muscle, or into a vein. This medicine can also be given as a shot into your back.
If a dose is missed:
  • This medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor or pharmacist for instructions.

How to Store and Dispose of This Medicine

  • If you store this medicine at home, keep it at room temperature, away from heat, moisture, and direct light.
  • After mixing, store the mixture in the refrigerator. Throw away any portion not used after 72 hours.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine, containers, and other supplies. You will also need to throw away old medicine after the expiration date has passed.
  • Keep all medicine away from children and never share your medicine with anyone.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine

  • Make sure your doctor knows if you are currently taking or have recently taken other antibiotics to treat or prevent an infection. Tell your doctor if you have recently had surgery or a procedure that included the use of anesthesia (medicine causing you to relax or fall asleep).
  • Make sure your doctor knows if you are pregnant.
  • Your doctor will need to check your blood or urine at regular visits while you are using this medicine. Be sure to keep all appointments.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:
  • Blurry vision.
  • Breathing problems or any change in how well you breathe.
  • Discomfort or trouble passing urine, or a decrease in how much or how often you pass urine.
  • Dizziness, drowsiness, or irritability.
  • Fever with a headache or stiff neck.
  • Loss of feeling in the arms or legs, tingling, weakness, or any trouble with movement.
If you notice these less serious side effects, talk with your doctor:
  • Increased warmth or redness (flushing) of the face.
  • Redness, pain, swelling, or a lump under your skin at the injection site.
  • White spots in your mouth or throat, vaginal itching, or unusual vaginal discharge (fluids).

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
Review Date: 2011-02-04 Reviewed By: Keywords: ,
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