Introduction

Fluorescein (FLURE-a-seen)

Helps certain parts of the eye become more visible during tests.

Brand Name(s)

There may be other brand names for this medicine.

Angioscein, AK-Fluor, Fluorescite

When This Medicine Should Not Be Used

You should not receive fluorescein if you have had an allergic reaction to it in the past.

How to Use This Medicine

Injectable

• A nurse or other trained health professional will give you this medicine. This medicine is given through a needle or catheter (flexible tube) into your vein.
• You may notice a strong taste in your mouth after fluorescein is injected. Your skin may have a yellowish discoloration for about 6 to 12 hours after your test. Your urine may appear bright yellow for up to 36 hours after your test.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine

• Make sure your doctor knows if you are pregnant or breast feeding, or if you have a history of asthma or allergies. Make sure your doctor knows if you have had an allergic reaction to any medicine or dye.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
• Dizziness, lightheadedness, fainting, or seizures (convulsions).
• Pain, redness, swelling, or peeling skin at the injection site, or pain or loss of feeling in the arm that the fluorescein was injected into.

If you notice these less serious side effects, talk with your doctor:

• Nausea, vomiting, stomach upset, abdominal (belly) pain.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088