Prilocaine (Injection)


Prilocaine (PRIL-oh-kane)
Local anesthetic that causes numbness (loss of feeling) in the mouth. Given before and during dental work to help prevent pain.

Brand Name(s)

There may be other brand names for this medicine.

Cinatest Plain, Citanest Plain Dental

When This Medicine Should Not Be Used

You should not receive this medicine if you have had an allergic reaction to prilocaine or certain other types of local anesthetic (numbing medicine). You should not receive this medicine if you have methemoglobinemia, a blood disorder.

How to Use This Medicine

  • A nurse or other trained health professional will give you this medicine. Your doctor will prescribe your exact dose and tell you how the medicine will be given.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
  • There are many other drugs that can interact with prilocaine. Make sure your doctor knows about all other medicines you are using.

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breast feeding, or if you have a history of glucose-6 phosphate deficiency (a blood disorder that causes anemia). Make sure your doctor knows if you have heart disease, heart rhythm problems, blood pressure problems, atherosclerosis (hardening of the arteries), or other circulation problems. Tell your doctor if you have liver disease, or any other health problems or drug allergies you may have.
  • Numbness may last for several hours after receiving this medicine. There is an increased risk of injury to your tongue, lips, and the inside of your cheeks until this medicine wears off. To avoid injury, do not chew solid foods until normal feeling has returned to the area. Do not test the feeling in your mouth by biting or poking at or in your mouth.
  • Make sure any doctor who treats you in the next week knows that you received this medicine. This medicine may affect the results of certain blood tests used to check your heart.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
  • Dizziness, lightheadedness, drowsiness, confusion (trouble thinking), seizures (convulsions), or fainting.
  • Loss of feeling or movement that lasts longer than your dentist told you to expect.
  • Loss of feeling or movement that happens somewhere else in your body other than the area that was numbed for treatment.
  • Skin rash, or skin turning pale gray, or blue color.
  • Swelling near the injection site.
  • Sudden or severe headache, or problems with vision, speech, or walking.
  • Tremors, shaking, chills, or unexplained sweating.
  • Uneven, pounding, fast, or slow heartbeats.
If you notice these less serious side effects, talk with your doctor:
  • Nausea or vomiting.
  • Restlessness or anxiety.
  • Ringing in the ears.
  • Vision changes.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
Review Date: 2011-02-04 Reviewed By: Keywords: ,
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