Methylergonovine (Injection)


Methylergonovine Maleate (meth-il-er-goe-NOE-veen MAL-ee-ate)
Prevents bleeding from the uterus that can happen after childbirth. Belongs to a class of drugs called ergot alkaloids.

Brand Name(s)

There may be other brand names for this medicine.


When This Medicine Should Not Be Used

You should not receive this medicine if you have had an allergic reaction to methylergonovine (Methergine®), or if you have high blood pressure. You should not receive this medicine if you are pregnant or if you have toxemia (high blood pressure during pregnancy).

How to Use This Medicine

  • Your doctor will prescribe your exact dose and tell you how often you should receive it. This medicine is given as a shot into one of your muscles or veins.
  • A nurse or other trained health professional will give you this medicine. This medicine is given after delivery of the placenta, or during the second stage of labor.
  • Your doctor may also prescribe methylergonovine tablets for you to take. Be sure to follow all your doctor's instructions.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
  • Make sure your doctor knows if you are also using other ergot medicines, such as ergotamine (Cafergot®, Ergomar®, Ergostat®), bromocriptine (Parlodel®), ergoloid mesylates (Hydergine®), or methysergide (Sansert®). Make sure your doctor knows if you are also using ephedrine, pseudoephedrine (Sudafed®), or phenylephrine (Neo-Synephrine®).

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breast feeding, or if you have sepsis (severe infection). Make sure your doctor knows if you have heart disease, or if you have kidney or liver problems.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
  • Blood clots.
  • Blood in your urine.
  • Chest pain.
  • Heart attack.
  • Seeing things that aren't there.
  • Seizures (convulsions).
  • Uneven heart beat.
If you notice these less serious side effects, talk with your doctor:
  • Confusion, weakness, or muscle twitching or cramping.
  • Funny or bad taste in your mouth.
  • Headache or stuffy nose.
  • Heavy sweating.
  • Lightheadedness, dizziness, or fainting.
  • Nausea, vomiting, or diarrhea.
  • Ringing in your ears.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
Review Date: 2011-02-04 Reviewed By: Keywords: ,
Adam Data Copyright The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only--they do not constitute endorsements of those other sites. © 1997- 2010 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

For information 410.787.4000

© 2015 UM Baltimore Washington Medical Center.  All rights reserved.

301 Hospital Drive, Glen Burnie, MD 21061 | 410-787-4000 | TTY 410-787-4498