Antihemophilic Factor VIII:C Human (an-tye-hee-moe-FIL-ik FAK-tor ATE C HUE-man), Von Willebrand Factor Complex (Human) (Von WILL-a-brand FAK-tor KOM-plex (HUE-man))
Controls and prevents bleeding in hemophilia A and von Willebrand disease.
There may be other brand names for this medicine.
When This Medicine Should Not Be Used
You should not use this medicine if you have had an allergic reaction to antihemophilic factor or von Willebrand factor complex.
How to Use This Medicine
- Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given through a needle placed in one of your veins.
- A nurse or other trained health professional will give you this medicine.
- You may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.
- This medicine is a powder that must be mixed with a special liquid (sterile water) before you use it. The sterile water will be in the same package with the powder. Let both the powdered medicine and the sterile water warm up to room temperature before you mix them together.
- After you mix the powdered medicine with the water, you must use the mixture within 3 hours.
- This medicine comes with patient instructions. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions.
If a dose is missed:
- Call your doctor or pharmacist for instructions.
How to Store and Dispose of This Medicine
- If you store this medicine at home, keep it in the refrigerator. Do not freeze.Do not freeze.
- After you mix the powder with the sterile water, do not store the mixture in the refrigerator. Keep the mixture at room temperature and use it within 3 hours.
- Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine, containers, and other supplies. You will also need to throw away old medicine after the expiration date has passed.
- Throw away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.
- Keep all medicine away from children and never share your medicine with anyone.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Warnings While Using This Medicine
- Make sure your doctor knows if you are pregnant or breastfeeding, or if you have ever had a blood clot or were given drugs called blood thinners (such as warfarin, Coumadin®).
- Make sure your doctor knows if you have a blood type of A, B, or AB.
- Your doctor will need to check your blood at regular visits while you are using this medicine. Be sure to keep all appointments.
- Make sure your doctor knows if you have received hepatitis A or hepatitis B vaccine shots.
- This medicine is made from donated human blood. Some human blood products have transmitted certain viruses to people who have received them. The risk of getting a virus from medicines made from human blood has been greatly reduced in recent years. This is the result of required testing of human donors for certain viruses, and testing by the company when these medicines are made. Although the risk is low, talk with your doctor if you have concerns.
Possible Side Effects While Using This Medicine
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Chest pain, coughing up of blood, or shortness of breath.
- Fever or chills.
- Numbness or weakness in your arm or leg, or on one side of your body.
- Pain or weakness in your lower leg (calf).
- Rapid weight gain or swelling in your hands, ankles, or feet.
- Sudden or severe headache, problems with speech, vision, or walking.
- Unusual bleeding or bruising.
- Yellowing of your skin or the whites of your eyes.
If you notice these less serious side effects, talk with your doctor:
- Itching or skin rash.
- Joint or muscle pain.
- Nausea, vomiting, or loss of appetite.
- Pain, itching, burning, swelling, or a lump under your skin where the needle is placed.