Enalaprilat (Injection)

Introduction

Enalaprilat (en-AL-a-pril-at)

Treats high blood pressure (hypertension). This medicine is an ACE inhibitor.

Brand Name(s)

There may be other brand names for this medicine.

When This Medicine Should Not Be Used

You should not use this medicine if you have had an allergic reaction to enalaprilat or to any ACE inhibitors such as Accupril®, Altace®, or Lotensin®. You should not use this medicine if you have a condition called hereditary angioedema. You should not use this medicine if you are pregnant.

How to Use This Medicine

Injectable

  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given through a needle placed in one of your veins.
  • A nurse or other trained health professional will give you this medicine.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are using diuretics ("water pills") such as amiloride, hydrochlorothiazide (HCTZ), furosemide, torsemide, Demadex®, Lasix®, spironolactone, triamterene, or Aldactone®.
  • Tell your doctor if you are using pain or arthritis medicine (sometimes called "NSAIDs") such as aspirin, diclofenac, ibuprofen, etodolac, indomethacin, piroxicam, naproxen, Advil®, Aleve®, Celebrex®, Feldene®, Indocin®, Relafen®, Motrin®, or Voltaren®.
  • Let your doctor know if you are using lithium, potassium supplements, or salt substitutes that contain potassium.
  • Make sure your doctor knows if you have ever been given a medicine to make you less sensitive to bee or ant stings.

Warnings While Using This Medicine

  • Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using the medicine, tell your doctor right away.
  • Make sure your doctor knows if you are breast feeding.
  • Make sure your doctor knows if you have diabetes, heart disease, kidney disease, or if you are on dialysis.
  • Tell your doctor if you have a collagen vascular disease such as lupus or arthritis.
  • This medicine lowers the number of some types of blood cells in your body. Because of this, you may bleed or get infections more easily. To help with these problems, avoid being near people who are sick or have infections. Wash your hands often. Stay away from rough sports or other situations where you could be bruised, cut, or injured. Brush and floss your teeth gently. Be careful when using sharp objects, including razors and fingernail clippers.
  • This medicine may make your skin more sensitive to sunlight. Use a sunscreen when you are outdoors. Avoid sunlamps and tanning beds.
  • Make sure any doctor or dentist who treats you knows that you are using this medicine. You may need to stop using this medicine several days before having surgery or medical tests.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
  • Blistering, peeling red skin rash, itching, or loss of hair.
  • Chest pain, uneven heartbeat, fast or slow heartbeat.
  • Decrease in how much or how often you urinate.
  • Lightheadedness or fainting.
  • Numbness or tingling in your hands, arms, legs, or feet, or muscle cramps.
  • Problems with walking or dizziness.
  • Trouble breathing or catching your breath.
  • Yellowing of your skin or the whites of your eyes.
  • Unusual bleeding, bruising, weakness, coughing up blood, or bloody, black tarry stools.

If you notice these less serious side effects, talk with your doctor:

  • Blurred vision, redness or watering of eyes, ringing in your ears, or loss of smell.
  • Burning pain while urinating.
  • Change in taste.
  • Cough, sore throat, or runny nose.
  • Depression, confusion, or headache.
  • Fever, fatigue, drowsiness, or lack of sleep.
  • Nausea, vomiting, constipation, thirst, or dry mouth.
  • Sweating, warmth, or redness in your chest, neck, or face.
  • Trouble having sex or increase in the size of breasts in men.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Review Date: 2011-02-04 Reviewed By: Keywords: ,
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