Eprosartan Mesylate (ep-roe-SAR-tan MES-i-late), Hydrochlorothiazide (hye-droe-klor-oh-THYE-a-zide)
Treats high blood pressure. This medicine is a combination of an antihypertensive (blood pressure medicine) and a diuretic ("water pill").
There may be other brand names for this medicine.
When This Medicine Should Not Be Used
You should not use this medicine if you have an allergy to eprosartan (Teveten®), hydrochlorothiazide (HCTZ), or sulfa drugs such as trimethoprim/sulfamethoxazole, Bactrim®, or Septra®. You should not use this medicine if you have problems with passing urine. You should not use this medicine if you are more than 12 weeks pregnant.
How to Use This Medicine
- Your doctor will tell you how much of this medicine to use and how often. Your dose may need to be changed several times in order to find out what works best for you. Do not use more medicine or use it more often than your doctor tells you to.
- You may take this medicine with or without food.
- Drink plenty of fluids while using this medicine.
If a dose is missed:
- If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.
How to Store and Dispose of This Medicine
- Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
- Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
- Keep all medicine away from children and never share your medicine with anyone.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- There are many other medicines that can interact with this medicine. Make sure your doctor knows about all other medicines you are using.
- Make sure your doctor knows if you are using any other blood pressure medicine. Tell your doctor if you use a diuretic ("water pill") such as furosemide, hydrochlorothiazide (HCTZ), spironolactone, or Lasix®.
- Tell your doctor if you use lithium, cholestyramine, colestipol, or Colestid®.
- Make sure your doctor knows if you use insulin or a diabetes medicine that you take by mouth such as glyburide, metformin, Actos®, or Glucotrol®. Make sure your doctor knows if you use pain or arthritis medicine such as aspirin, ibuprofen, Advil®, Aleve®, or Celebrex®.
- Tell your doctor if you use a steroid medicine such as dexamethasone, prednisolone, prednisone, Decadron®, or Medrol®.
- You should not use potassium tablets or salt substitutes that contain potassium unless you talk to your doctor.
- Do not drink alcohol while you are using this medicine.
Warnings While Using This Medicine
- Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using the medicine, tell your doctor right away.
- Make sure your doctor knows if you are breast feeding.
- Make sure your doctor knows if you have liver disease, kidney disease, or heart disease. Tell your doctor if you have lupus, gout, asthma or diabetes.
- Your doctor will need to check your blood or urine at regular visits while you are using this medicine. Be sure to keep all appointments.
- This medicine may raise or lower your blood sugar, or it may cover up symptoms of very low blood sugar (hypoglycemia).
- Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may affect the results of certain medical tests.
Possible Side Effects While Using This Medicine
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
- Blistering, peeling, or red skin rash.
- Change in how much or how often you pass urine, or bloody urine.
- Chest pain, fast or uneven heartbeat.
- Confusion, dizziness, weakness, muscle twitching.
- Numbness and tingling in your hands, arms, feet, or lips.
- Lightheadedness or fainting.
- Sudden and severe stomach pain, nausea, vomiting, fever.
- Swelling in your hands, ankles, or feet.
- Unusual bleeding, bruising, or weakness.
- Yellowing of your skin or the whites of your eyes.
If you notice these less serious side effects, talk with your doctor:
- Bleeding gums or tooth ache.
- Blurred vision.
- Dry mouth, increased thirst, constipation, or loss of appetite.
- Fever, chills, sore throat, or cough.
- Headache or fatigue.
- Joint pains or back pain.
- Trouble having sex (in men).
- Trouble sleeping or ringing in ears.
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
Review Date: 2011-02-04