Hydrochlorothiazide (hye-droe-klor-oh-THYE-a-zide), Olmesartan Medoxomil (ol-me-SAR-tan me-DOX-oh-mil)
Treats high blood pressure. A lower blood pressure can reduce the risk of stroke and heart attack. This medicine is a combination of an angiotensin receptor blocker (ARB) and a diuretic (water pill).
There may be other brand names for this medicine.
When This Medicine Should Not Be Used
Do not use this medicine if you have had an allergic reaction to olmesartan, hydrochlorothiazide, or sulfa drugs. Do not use this medicine if you are pregnant or not able to urinate. Do not use this medicine together with aliskiren (Tekturna®) if you have diabetes.
How to Use This Medicine
- Your doctor will tell you how much of this medicine to use and how often. Your dose may need to be changed several times in order to find out what works best for you. Do not use more medicine or use it more often than your doctor tells you to.
- Carefully follow your doctor's instructions about any special diet.Be sure to drink plenty of fluids if you exercise, sweat more than usual, or have diarrhea or vomiting.
If a dose is missed:
- If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.
How to Store and Dispose of This Medicine
- Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
- Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
- Keep all medicine away from children and never share your medicine with anyone.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Make sure your doctor knows if you also use other blood pressure medicines, including diuretics or water pills, such as furosemide, metolazone, spironolactone, triamterene, Aldactone®, Demadex®, or Lasix®.
- Make sure your doctor knows if you also use lithium (Eskalith®, Lithobid®), medicine to lower cholesterol (such as cholestyramine, colestipol, Colestid®, Questran®), insulin or diabetes medicine that you take by mouth (such as glimepiride, glyburide, metformin, Actos®, Janumet®, Januvia®), a steroid medicine (such as dexamethasone, hydrocortisone, methylprednisolone, prednisolone, prednisone, Medrol®), or an NSAID pain or arthritis medicine (such as aspirin, diclofenac, ibuprofen, naproxen, Advil®, Aleve®, Celebrex®, Voltaren®).
- If you also use colesevelam (Welchol®), take it at least 4 hours after you take Benicar HCT®.
- Ask your doctor before you use any medicine, supplement, or salt substitute that contains potassium.
- Alcohol, narcotic pain relievers, or sleeping pills may cause you to feel more lightheaded, dizzy, or faint when used with this medicine.
Warnings While Using This Medicine
- Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using the medicine, tell your doctor right away.
- Make sure your doctor knows if you are breastfeeding or if you have kidney problems, liver disease (including cirrhosis), congestive heart failure, diabetes, glaucoma, gout, high cholesterol, a mineral imbalance (such as high or low calcium, potassium, magnesium, or sodium in the blood), lupus, or asthma.
- This medicine could lower your blood pressure too much and cause you to feel dizzy or lightheaded. Stand or sit up slowly if you are dizzy. This is more likely to happen when you begin to use the medicine. It could also happen if you have diarrhea or vomiting, you sweat heavily, or you do not drink enough water and become dehydrated.
- This medicine may make you drowsy. Do not drive, use machines, or do anything else that could be dangerous until you know how this medicine affects you.
- Check with your doctor immediately if you have vision changes, such as blurred vision, difficulty reading, or eye pain, during or after treatment. This could be a sign of a serious eye problem.
- Your doctor will need to check your blood or urine at regular visits while you are using this medicine. Be sure to keep all appointments.
- Do not stop using the medicine without asking your doctor, even if you feel well. This medicine will not cure your high blood pressure, but it will help keep it in normal range. You may have to take blood pressure medicine for the rest of your life.
Possible Side Effects While Using This Medicine
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blistering, peeling, or red skin rash
- Blurred vision or changes in vision
- Change in how much or how often you urinate, bloody or cloudy urine
- Confusion, weakness, and muscle twitching
- Dry mouth, increased thirst, muscle cramps, nausea, vomiting
- Fast, slow, or uneven heartbeat, chest pain
- Lightheadedness, dizziness, fainting
- Yellow skin or eyes
If you notice these less serious side effects, talk with your doctor:
- Cough, runny or stuffy nose, sore throat