Tiopronin (By mouth)

Introduction

Tiopronin (tye-oh-PROE-nin)

Prevents kidney stones.

Brand Name(s)

There may be other brand names for this medicine.

Thiola

When This Medicine Should Not Be Used

You should not use this medicine if you have had an allergic reaction to tiopronin. You should not use this medicine if you have had a blood disorder such as aplastic anemia after using tiopronin. You should not use this medicine if you are pregnant or breast feeding.

How to Use This Medicine

  • Your doctor will tell you how much of this medicine to use and how often. Your dose may need to be changed several times in order to find out what works best for you. Do not use more medicine or use it more often than your doctor tells you to.
  • Drink extra fluids so you will pass more urine while you are using this medicine. This will keep your kidneys working well and help prevent kidney problems.
  • If you awaken during the night to use the bathroom, drink 2 glasses of water before going back to bed.
  • Take this medicine one hour before or two hours after a meal.

If a dose is missed:

  • If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine after you have finished your treatment. You will also need to throw away old medicine after the expiration date has passed.
  • Keep all medicine away from children and never share your medicine with anyone.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using penicillamine (Cuprimine®, Depen®).

Warnings While Using This Medicine

  • Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using the medicine, tell your doctor right away.
  • Make sure your doctor knows if you have kidney disease, myasthenia gravis, or Goodpasture's syndrome. Make sure your doctor knows if you have any blood disorders such as agranulocytosis, thrombocytopenia, or aplastic anemia.
  • Your doctor will need to check your blood or urine at regular visits while you are using this medicine. Be sure to keep all appointments.
  • Your doctor will need to check your progress at regular visits while you are using this medicine. Be sure to keep all appointments.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
  • Blood in your urine, change in how much and how often you urinate.
  • Chest tightness, coughing up of blood, or trouble breathing.
  • Fever, chills, cough, sore throat, body aches.
  • Lumps in your body such as in armpits, neck, or thighs.
  • Severe muscle weakness.
  • Severe vomiting, diarrhea, or stomach pain.
  • Unusual bleeding, bruising, or weakness.
  • Yellowing of your skin or whites of your eyes.

If you notice these less serious side effects, talk with your doctor:

  • Joint pain or muscle pain.
  • Nausea, mild stomach pain, diarrhea, loss of appetite.
  • Mild skin rash or itching.
  • Reduced taste sensation.
  • Skin changes.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Review Date: 2011-02-04 Reviewed By: Keywords: ,
Adam Data Copyright The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only--they do not constitute endorsements of those other sites. © 1997- 2010 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

For information 410.787.4000

© 2013 UM Baltimore Washington Medical Center.  All rights reserved.

301 Hospital Drive, Glen Burnie, MD 21061 | 410-787-4000 | TTY 410-787-4498