Iodine I 131 tositumomab (Injection)

Introduction

Iodine I 131 Tositumomab (EYE-oh-din I 131 tos-IT-too-moe-mab)

Treats non-Hodgkin's lymphoma.

Brand Name(s)

There may be other brand names for this medicine.

Bexxar

When This Medicine Should Not Be Used

You should not receive this medicine if you have had an allergic reaction to iodine I 131 tositumomab. You should not receive this medicine if you are pregnant or breast feeding.

How to Use This Medicine

Injectable

  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given through a needle placed in one of your veins.
  • You will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.
  • This medicine comes with patient instructions. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions.
  • Medicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are using aspirin, warfarin, or Coumadin®.
  • Talk to your doctor before getting flu shots or other vaccines while you are receiving this medicine. Vaccines may not work as well, or they could make you ill while you are using this medicine.

Warnings While Using This Medicine

  • This medicine can cause birth defects if it is used by the mother while she is pregnant or by the father when his sexual partner becomes pregnant. If a pregnancy occurs while you are using this medicine, tell your doctor right away. Use an effective form of birth control to keep from getting pregnant.
  • If you plan to have children, talk with your doctor before using this medicine. Some men and women using this medicine have become infertile (unable to have children).
  • Make sure your doctor knows if you have kidney disease or thyroid disease.
  • This medicine may increase your risk of certain types of cancer. Talk with your doctor about this risk.
  • You will be exposed to dangers of radiation while using this medicine. Talk to your doctor about this risk and the precautions that you might need to take.
  • Cancer medicines can cause nausea and/or vomiting in most people, sometimes even after receiving medicines to prevent it. Ask your doctor or nurse about other ways to control these side effects.
  • Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may affect the results of certain medical tests.
  • This medicine lowers the number of some types of blood cells in your body. Because of this, you may bleed or get infections more easily. To help with these problems, avoid being near people who are sick or have infections. Wash your hands often. Stay away from rough sports or other situations where you could be bruised, cut, or injured. Brush and floss your teeth gently. Be careful when using sharp objects, including razors and fingernail clippers.
  • Your doctor will need to check your blood at regular visits while you are using this medicine. Be sure to keep all appointments.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
  • Chest pain or shortness of breath.
  • Light-headedness, dizziness, or fainting.
  • Rapid weight gain.
  • Swelling in your face, hands, ankles, or feet.
  • Unusual bleeding, bruising, or weakness.

If you notice these less serious side effects, talk with your doctor:

  • Fever, chills, cough, sore throat, or body aches.
  • Nausea, vomiting, diarrhea, constipation, or loss of appetite.
  • Pain, itching, burning, swelling, or a lump under your skin where the needle is placed.
  • Sweating or muscle weakness.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Review Date: 2011-02-04 Reviewed By: Keywords: ,
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