Solifenacin (By mouth)

Introduction

Solifenacin (soe-li-FEN-a-sin)

Treats symptoms of overactive bladder, such as an increased need to urinate, passing urine more often, or loss of bladder control (incontinence).

Brand Name(s)

There may be other brand names for this medicine.

VESIcare, Vesicare

When This Medicine Should Not Be Used

You should not use this medicine if you have had an allergic reaction to solifenacin, or if you have problems passing urine, if you have uncontrolled narrow-angle glaucoma, or if you have problems with food emptying from your stomach (gastric retention).

How to Use This Medicine

Tablet

  • Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to.
  • Take this medicine with liquid. Swallow the tablet whole. Do not break, crush, or chew it.
  • You may take this medicine with or without food.
  • This medicine comes with patient instructions. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions.

If a dose is missed:

  • If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine after you have finished your treatment. You will also need to throw away old medicine after the expiration date has passed.
  • Keep all medicine away from children and never share your medicine with anyone.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using atazanavir (Reyataz®), clarithromycin (Biaxin®), indinavir (Crixivan®), itraconazole (Sporanox®), ketoconazole (Nizoral®), nefazodone (Serzone®), nelfinavir (Viracept®), ritonavir (Norvir®), saquinavir (Invirase®), telithromycin (Ketek®), or voriconazole (Vfend®).
  • Make sure your doctor knows if you are also using arsenic trioxide (Trisenox®), cisapride (Propulsid®), dofetilide (Tikosyn®), medicine for depression (such as amitriptyline, fluoxetine, nortriptyline, Elavil®, Pamelor®, Prozac®, Sarafem®, or Vivactil®), certain antibiotics (such as erythromycin, levofloxacin, moxifloxacin, sparfloxacin, Avelox®, Levaquin®, or Zagam®), or medicine to treat mental illness (such as haloperidol, mesoridazine, pimozide, prochlorperazine, quetiapine, thioridazine, ziprasidone, Compazine®, Geodon®, Haldol®, Mellaril®, Orap®, Serentil®, or Seroquel®).

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, a bladder blockage (hard to urinate), heart rhythm problems (such as QT prolongation), narrow-angle glaucoma, or stomach or bowel problems such as constipation.
  • This medicine may cause a serious type of allergic reaction called angioedema. Angioedema may be life-threatening and requires immediate medical attention. Stop taking this medicine and check with your doctor right away if you have a rash; itching; a large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs; trouble with breathing; or chest tightness while you are using this medicine.
  • This medicine may cause constipation, call your doctor if you get severe stomach pain or become constipated for 3 or more days.
  • This medicine may make you sweat less, causing your body temperature to increase. Use extra care not to become overheated during exercise or hot weather while you are taking this medicine, since overheating may result in heat stroke.
  • This medicine may cause blurred vision. Avoid driving, using machines, or doing anything else that could be dangerous if you are not able to see clearly. You may have to take the medicine for a few days before you know how it will affect you.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
  • Change in how much or how often you urinate, or painful urination.
  • Constipation that lasts for 3 days or longer.
  • Fever, chills, cough, sore throat, and body aches.
  • Severe stomach pain.
  • Swelling in your legs, ankles, or feet.

If you notice these less serious side effects, talk with your doctor:

  • Blurred vision.
  • Decreased sweating.
  • Dizziness.
  • Dry eyes or mouth.
  • Feeling tired.
  • Mild constipation.
  • Nausea, vomiting, or stomach pain or upset.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Review Date: 2011-02-04 Reviewed By: Keywords: ,
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