Treats leukemia. This is a cancer medicine.
There may be other brand names for this medicine.
When This Medicine Should Not Be Used
You should not receive this medicine if you have had an allergic reaction to clofarabine, or if you are pregnant.
How to Use This Medicine
- Medicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.
- You will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.
- Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given through a needle placed in one of your veins.
If a dose is missed:
- This medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Warnings While Using This Medicine
- Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using the medicine, tell your doctor right away.
- Make sure your doctor knows if you are breastfeeding, or if you have kidney or liver disease. Tell your doctor if you have had a hematopoietic stem cell transplant (HSCT).
- This medicine lowers the number of some types of blood cells in your body. Because of this, you may bleed or get infections more easily. To help with these problems, avoid being near people who are sick or have infections. Wash your hands often. Stay away from rough sports or other situations where you could be bruised, cut, or injured. Brush and floss your teeth gently. Be careful when using sharp objects, including razors and fingernail clippers.
- This medicine may cause high uric acid levels in the blood or tumor lysis syndrome. Call your doctor right away if you have a decrease or change in urine amount, joint pain, stiffness, or swelling, lower back, side, or stomach pain, rapid weight gain, swelling of the feet or lower legs, or unusual tiredness or weakness.
- Call your doctor right away if you have dizziness, faintness, or lightheadedness, a fast or uneven heartbeat, trouble breathing, or swelling of the hands, ankles, feet, or lower legs. These may be symptoms of rare but serious conditions called capillary leak syndrome or systemic inflammatory response syndrome (SIRS).
- Check with your doctor right away if you have stomach pain, pale stools or dark urine, loss of appetite, or yellow eyes or skin. These could be symptoms of a serious liver problem.
- Cancer medicines can cause nausea and/or vomiting in most people, sometimes even after receiving medicines to prevent it. Ask your doctor or nurse about other ways to control these side effects.
- Your doctor will need to check your blood or urine at regular visits while you are using this medicine. Be sure to keep all appointments.
Possible Side Effects While Using This Medicine
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blistering, peeling, or red skin rash
- Blue lips and fingernails, increased sweating, pale skin
- Change in how much or how often you urinate
- Chest tightness, trouble breathing, rapid shallow breathing
- Dark urine or pale stools, loss of appetite, pain in your upper stomach, yellow skin or eyes
- Fast, pounding, or uneven heartbeat
- Fever, chills, cough, sore throat, and body aches
- Lightheadedness, dizziness, or fainting
- Rapid weight gain, swelling of your hands, ankles, feet, or face
- Red or brown urine
- Unusual bleeding, bruising, or weakness
If you notice these less serious side effects, talk with your doctor:
- Nosebleeds, bleeding from your gums
- Pain, itching, burning, swelling, or a lump under your skin where the needle is placed
- Small red spots under your skin, rash, or itchy skin
- Vomiting, diarrhea, stomach pain, loss of appetite
- Warmth or redness of your face, neck, arm, or upper chest