Esomeprazole (Injection)

Introduction

Esomeprazole (es-oh-MEP-ra-zole)

Treats gastroesophageal reflux disease (GERD) in patients who are temporarily unable to take the oral form of this medicine. This medicine is a proton pump inhibitor (PPI).

Brand Name(s)

There may be other brand names for this medicine.

Nexium I.V.

When This Medicine Should Not Be Used

You should not receive this medicine if you have had an allergic reaction to esomeprazole or to similar medicines such as omeprazole (Prilosec®), lansoprazole (Prevacid®), pantoprazole (Protonix®), or rabeprazole (Aciphex®).

How to Use This Medicine

Injectable

  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given through a needle placed in one of your veins.
  • A nurse or other trained health professional will give you this medicine.
  • Your doctor will give you a few doses of this medicine until your condition improves, and then switch you to an oral medicine that works the same way. If you have any concerns about this, talk to your doctor.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using medicine to treat HIV infection (such as atazanavir, nelfinavir, saquinavir, Fortovase®, Invirase®, Reyataz®, or Viracept®), cilostazol (Pletal®), digoxin (Lanoxin®), ketoconazole (Nizoral®), voriconazole (Vfend®), iron supplements, or a blood thinner (such as warfarin, Coumadin®).

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have liver disease or bone problems (such as osteoporosis).
  • This medicine may increase your risk of having fractures of the hip, wrist, and spine. This is more likely if you are 50 years of age and older, if you receive high doses of this medicine, or use it for one year or more.
  • Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may affect the results of certain medical tests.
  • Your doctor will need to check your progress at regular visits while you are using this medicine. Be sure to keep all appointments.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
  • Blistering, peeling, or red skin rash.
  • Bloody or black, tarry stools.
  • Chest pain, fast heartbeat, sweating, or warmth or redness in your face or upper chest.
  • Confusion, depressed mood.
  • Fever, chills, cough, sore throat, and body aches.
  • Increase in how much or how often you urinate.
  • Redness, pain, itching, swelling, or a lump under your skin where the needle is placed.
  • Shortness of breath, wheezing.
  • Swelling in your hands, ankles, or feet.
  • Unusual bleeding, bruising, weakness, or pale skin.
  • Vomiting of blood or material that looks like coffee grounds.
  • Yellowing of your skin or the whites of your eyes.

If you notice these less serious side effects, talk with your doctor:

  • Changes in your menstrual periods.
  • Constipation, diarrhea, nausea, gas, or stomach pain or upset.
  • Dry mouth, increased or decreased appetite.
  • Headache, dizziness, ear pain, or ringing in your ears.
  • Joint pain.
  • Mild skin rash or itching.
  • Runny or stuffy nose.
  • Weight gain or loss.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Review Date: 2011-02-04 Reviewed By: Keywords: ,
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