Idursulfase (Injection)

Introduction

Idursulfase (eye-dur-SUL-fase)

Improves walking ability in people with an enzyme deficiency called mucopolysaccharidosis II (MPS II) or Hunter syndrome.

Brand Name(s)

There may be other brand names for this medicine.

Elaprase

When This Medicine Should Not Be Used

You should not use this medicine if you have had an allergic reaction to idursulfase.

How to Use This Medicine

Injectable

  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given through a needle placed in one of your veins.
  • The usual dose schedule for this medicine is one time each week. The medicine is given slowly, so the needle will remain in place for more than an hour.
  • A nurse or other trained health professional will give you this medicine.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have lung disease or any breathing problems.
  • Some people who have used this medicine developed serious allergic reactions while receiving the medicine. Ask your doctor about this if you have any concerns.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
  • Changes in vision.
  • Chest pain, shortness of breath, or coughing up blood.
  • Fast, slow, or irregular heartbeat.
  • Fever.
  • Lightheadedness or fainting.
  • Pain, itching, burning, swelling, or a lump under your skin where the needle is placed.
  • Seizures.
  • Swelling with pus.
  • Trouble breathing, wheezing, or bluish-colored skin or nailbeds.
  • Unusual tiredness or weakness.

If you notice these less serious side effects, talk with your doctor:

  • Anxiety, irritability.
  • Headache.
  • Mild skin rash, itching, or redness.
  • Muscle or joint pain, or arm or leg pain.
  • Upset stomach.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Review Date: 2011-02-04 Reviewed By: Keywords: ,
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