Panitumumab (Injection)

Introduction

Panitumumab (pan-i-TOOM-ue-mab)

Treats cancer of the colon or rectum. This medicine may be given in patients who have already received other cancer medicines.

Brand Name(s)

There may be other brand names for this medicine.

Vectibix

When This Medicine Should Not Be Used

You should not receive this medicine if you have had an allergic reaction to panitumumab.

How to Use This Medicine

Injectable

  • Medicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.
  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given through a needle placed in one of your veins. This medicine needs to be given slowly, so the needle will remain in place for at least an hour.
  • You will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.

If a dose is missed:

  • This medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine

  • Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using the medicine, tell your doctor right away. Continue to use an effective form of birth control for 6 months after the last dose.
  • Make sure your doctor knows if you are breastfeeding, or if you have lung problems or trouble with breathing.
  • This medicine may cause serious skin problems that may lead to infections that may become life-threatening. Tell your doctor right away if you have a skin rash, itchiness, skin redness or swelling, dry skin, peeling skin or fissures, or fingernail changes while using this medicine.
  • This medicine may cause a serious side effect called an infusion reaction. This can be life-threatening and require immediate medical attention. Tell your doctor or nurse right away if you have fever, chills, trouble with breathing, chest tightness, swelling in your face or hands, lightheadedness, or if you feel like fainting within a few hours after you receive it.
  • Check with your doctor right away if you have any changes to your eyes, such as redness, itching, swelling, or vision changes while you are using this medicine. Your doctor may want you to have your eyes checked by an eye doctor.
  • This medicine may cause diarrhea and dehydration when used with other cancer medicines. This may also cause you to have an electrolyte problem, such as low magnesium, potassium, or calcium in the blood. Tell your doctor right away if you start having muscle cramps or twitching, mood or mental changes, or unusual tiredness or weakness while using this medicine.
  • Your doctor will need to check your blood at regular visits while you are using this medicine. Be sure to keep all appointments.
  • This medicine may make your skin more sensitive to sunlight. Use a sunscreen when you are outdoors. Avoid sunlamps and tanning beds. Wear protective clothing and hats while receiving this medicine and for 2 months after the last dose.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
  • Acne, fingernail changes, or skin dryness, itchiness, or fissures.
  • Blistering, peeling, or red skin rash.
  • Confusion, weakness, and muscle twitching.
  • Dry mouth, increased thirst, or muscle cramps.
  • Eye redness or pain, tearing, or changes in vision.
  • Fever and chills.
  • Lightheadedness or fainting.
  • Pain, itching, burning, swelling, or a lump under your skin where the needle is placed.
  • Rapid weight gain.
  • Shortness of breath or chest tightness.
  • Swelling in your hands, ankles, or feet.

If you notice these less serious side effects, talk with your doctor:

  • Cough.
  • Nausea, vomiting, diarrhea, constipation, or stomach pain.
  • Sores or white patches on your lips, mouth, or throat.
  • Weakness or tiredness.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Review Date: 2011-02-04 Reviewed By: Keywords: ,
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