Treats schizophrenia, as well as the agitation that sometimes happens with schizophrenia or bipolar disorder.
There may be other brand names for this medicine.
Abilify, Abilify Maintena
When This Medicine Should Not Be Used
Do not receive this medicine if you have had an allergic reaction to aripiprazole.
How to Use This Medicine
- Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot into one of your muscles.
- A nurse or other trained health professional will give you this medicine.
- Regular injection: Your doctor will give you a few doses until your condition improves, and then switch you to an oral medicine that works the same way. If you have any concerns about this, talk to your doctor.
- Extended-release injection: At first, this medicine is given together with oral medicine. The second injection dose is given 1 month after the first one, without oral medicine. The injections that follow are once a month instead of oral medicine.
- This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions. Ask your pharmacist for the Medication Guide if you do not have one.
If a dose is missed:
- Extended-release injection: This medicine needs to given on a fixed schedule. Call your doctor or pharmacist for instructions.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Tell your doctor if you are also using carbamazepine (Tegretol®), clarithromycin (Biaxin®), fluoxetine (Prozac®), ketoconazole (Nizoral®), paroxetine (Paxil®), or quinidine (Cardioquin®, Quinaglute®). Tell your doctor if you are also using certain medicines for high blood pressure, such as doxazosin, terazosin, Cardura®, Hytrin®.
- Tell your doctor if you are using any medicines that make you sleepy. These include sleeping pills, cold and allergy medicine, narcotic pain relievers, and sedatives.
- Do not drink alcohol while you are using this medicine.
Warnings While Using This Medicine
- Make sure your doctor knows if you are pregnant or breastfeeding, have a history of seizures, or have experienced symptoms of neuroleptic malignant syndrome (NMS) in the past. Tell your doctor if you have history of heart attack, stroke, heart failure, heart or blood vessel disease, heart rhythm problems, high or low blood pressure, or high cholesterol.
- This medicine should not be used to treat Alzheimer disease or dementia in elderly adults because of an increased risk for stroke and other side effects.
- Tell your doctor if you have diabetes because this medicine may raise your blood sugar. You may need to check your blood sugar more often.
- Check with your doctor right away if you have twitching or muscle movements you cannot control (often in your face, tongue, or jaw). These could be symptoms of a movement disorder called tardive dyskinesia. This disorder may not go away, even after you stop taking this medicine.
- Check with your doctor right away if you have a high fever, sweating, confusion, uneven heartbeat, or muscle stiffness. These could be symptoms of a serious condition called neuroleptic malignant syndrome (NMS).
- This medicine may make you dizzy or drowsy. Do not drive, use machines, or do anything else that could be dangerous until you know how this medicine affects you. Stand or sit up slowly if you feel lightheaded or dizzy.
- This medicine lowers the number of some types of blood cells in your body. Because of this, you may bleed or get infections more easily. To help with these problems, avoid being near people who are sick or have infections. Wash your hands often. Stay away from rough sports or other situations where you could be bruised, cut, or injured. Brush and floss your teeth gently. Be careful when using sharp objects, including razors and fingernail clippers.
- You may get overheated more easily while you use this medicine. Be careful if you exercise often or are in high heat or humidity. Drink plenty of water and stay out of the sun. If your body gets too hot, you might feel dizzy, weak, tired, or confused. You might vomit or have an upset stomach.
- For some children, teens, and young adults, this medicine can increase thoughts of suicide. Tell your doctor right away if the person who takes this medicine becomes very depressed or has suicidal thoughts. Report any new, unusual, or worsening thoughts or behaviors, such as trouble sleeping, anxiety or panic attacks, sudden mood changes, or sudden increases in energy. Also report violent behavior or dangerous impulses. Tell your doctor if you or anyone in your family has bipolar disorder or has tried to commit suicide.
- Your doctor will need to check your blood or urine at regular visits while you are using this medicine. Be sure to keep all appointments.
Possible Side Effects While Using This Medicine
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Anxiety, irritability, nervousness, restlessness, trouble sleeping
- Change in how much or how often you urinate
- Chest pain, fast or slow heartbeat
- Confusion, unusual behavior, depressed mood, thoughts of hurting self or others
- Fever, chills, cough, sore throat, and body aches
- Fever, sweating, confusion, uneven heartbeat, muscle stiffness
- Jerky muscle movement you cannot control (often in your face, tongue, or jaw)
- Lightheadedness, dizziness, or fainting
- Seizures or tremors
- Severe drowsiness or sleepiness
- Trouble swallowing
- Unusual bleeding or bruising
- Unusual tiredness or weakness
If you notice these less serious side effects, talk with your doctor:
- Redness, pain, swelling, itching, blistering, or rash where the shot was given
- Weight gain or loss