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Telbivudine (By mouth)
Treats chronic hepatitis B infection. This is an antiviral medicine.
There may be other brand names for this medicine.
When This Medicine Should Not Be Used
You should not use this medicine if you have had an allergic reaction to telbivudine.
How to Use This Medicine
- Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to.
- You may take this medicine with or without food.
- Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.
- The oral solution contains sodium. Ask your doctor for advice if you are on a low sodium diet.
- This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions. Ask your pharmacist for the Medication Guide if you do not have one. Your doctor might ask you to sign some forms to show that you understand this information.
- This medicine comes with patient instructions. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions.
- This medicine works best if there is a constant amount in the blood. To keep blood levels constant, take this medicine at the same time each day and do not miss any doses.
If a dose is missed:
- If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.
How to Store and Dispose of This Medicine
- Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
- Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine after you have finished your treatment. You will also need to throw away old medicine after the expiration date has passed.
- Throw away any unused oral solution 60 days after opening the bottle. Unused or outdated medicine should not be put directly in the trash can. Place it in a closed container first, such as a sealed bag, then into the household trash. You may also take it to a community take-back program when available.
- Keep all medicine away from children and never share your medicine with anyone.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Make sure your doctor knows if you are also using pegylated interferon alfa-2a (Pegasys®) or any interferon injection product.
Warnings While Using This Medicine
- Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease, myopathy (muscle problem), or peripheral neuropathy (nerve disorder with numbness, tingling).
- Two rare but serious reactions to this medicine are lactic acidosis (too much acid in the blood) and liver toxicity, which includes an enlarged liver. These are more common if you are female, very overweight (obese), or have been taking anti-HIV medicines for a long time. Call your doctor right away if you have more than one of these symptoms: abdominal discomfort or cramping; dark urine; decreased appetite; diarrhea; a general feeling of discomfort; light-colored stools; muscle cramping or pain; nausea; unusual tiredness or weakness; trouble with breathing; vomiting; or yellow eyes or skin.
- Hepatitis B infection may become worse if this medicine is stopped too soon. Do not stop taking this medicine without first checking with your doctor. When you are told to stop taking this medicine, you may need to see your doctor on a regular basis to check your liver. Keep all appointments.
- Some patients who have used this medicine had unexplained muscle aches, pain, tenderness, or weakness. If you notice any of these symptoms, call your doctor right away.
- This medicine is not a cure for the hepatitis B virus, but it may lower the amount of virus in your body and keep you from making more of the virus.
- This medicine will not keep you from giving the hepatitis B virus to your partner during sex. Make sure you understand this and practice safe sex, even if your partner also has hepatitis B. The male partner should use a latex condom during sex. Do not share needles and personal items, such as toothbrushes or razor blades, that can have blood or body fluids on them with anyone.
- Your doctor will need to check your blood or urine at regular visits while you are using this medicine. Be sure to keep all appointments.
Possible Side Effects While Using This Medicine
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
- Dark-colored urine or pale stools.
- Extreme weakness, tiredness, or confusion.
- Fever, chills, cough, sore throat, runny or stuffy nose, and body aches.
- Lightheadedness or fainting.
- Nausea, vomiting, loss of appetite, or pain in your upper stomach.
- Numbness, tingling, or burning pain in your hands, arms, legs, or feet.
- Rapid breathing or trouble with breathing.
- Unexplained muscle aches, pain, tenderness, or weakness.
- Yellowing of your skin or the whites of your eyes.
If you notice these less serious side effects, talk with your doctor:
- Back or joint pain.
- Diarrhea or stomach upset.
- Loss of appetite.
- Skin rash.
- Trouble with sleeping.
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
Review Date: 2011-02-04 Reviewed By: Keywords: ,
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