Diphtheria/tetanus/acellular pertussis/polio vaccine (Injection)


Diphtheria Toxoid, Adsorbed (dif-THEER-ee-a TOX-oyd, ad-SORBD), Pertussis Vaccine, Acellular (per-TUS-iss VAX-een, a-SELL-yoo-lar), Poliovirus Vaccine, Inactivated (POE-lee-oh VYE-rus VAX-een, in-AK-ti-vated), Tetanus Toxoid (TET-n-us TOX-oyd)
Protects children against infections caused by diphtheria, tetanus (lockjaw), pertussis (whooping cough), and polio. This vaccine is given only to children 4 to 6 years of age, and is given before the child's 7th birthday.

Brand Name(s)

There may be other brand names for this medicine.

Pentacel, Kinrix

When This Medicine Should Not Be Used

This vaccine should not be given to a child who has had an allergic reaction to the separate or combined diphtheria, tetanus, pertussis, or polio vaccines, or to a child who has had an allergic reaction to neomycin or polymyxin B. Do not give this vaccine to a child who has had seizures or collapsed within 7 days after receiving a pertussis vaccine. This vaccine should not be given to a child who has certain nervous system problems or seizures that are not under control.

How to Use This Medicine

  • Your doctor will prescribe your child's exact dose. A nurse or other trained health professional will give your child this vaccine. This vaccine is given as a shot into one of your child's muscles, usually in the shoulder muscle.
  • Your child may receive other vaccines at the same time as this one, but in a different body area. You should receive patient information sheets about all of the vaccines. Make sure you understand all of the information that is given to you.
  • Your child may also receive medicines to help prevent or treat some minor side effects of the vaccine, such as fever and soreness.
If a dose is missed:
  • If this vaccine is part of a series of vaccines, it is important that your child receive all of the shots. Try to keep all scheduled appointments. If your child must miss a shot, make another appointment with the doctor as soon as possible.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
  • Make sure your doctor knows if your child is having radiation treatments or using a medicine that weakens the immune system, such as a steroid or cancer medicine. This vaccine may not work as well if your child has a weak immune system.

Warnings While Using This Medicine

  • Make sure your doctor knows if your child has been sick or had a fever recently. Tell your doctor about any reaction your child has had after receiving any type of vaccine. This includes fainting, seizures, a fever over 105 degrees F, crying that would not stop, or severe redness or swelling where the shot was given. Tell your doctor if your child has had Guillain-Barre syndrome (nerve disease that causes paralysis) after a tetanus vaccine.
  • Make sure your doctor knows if your child is allergic to latex rubber. One of the prefilled syringes for this vaccine contains dry natural latex rubber. This may cause an allergic reaction in children who are sensitive to latex.
  • Tell your child's doctor about all other vaccines your child has had. This vaccine might be used to finish a series of vaccines.
  • This vaccine will not treat an active infection. If your child has an infection due to diphtheria, tetanus, pertussis, or polio, your child will need medicines to treat these infections.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
  • Bluish-colored skin, lips, or nailbed.
  • Crying constantly for 3 hours or more.
  • Decrease in how much or how often you urinate.
  • Dry mouth, increased thirst.
  • Fever over 105 degrees F.
  • Lightheadedness or fainting.
  • Nausea, vomiting, diarrhea, constipation, or stomach pain.
  • Seizures.
  • Severe headache.
  • Severe muscle weakness or numbness.
  • Swollen, painful, or tender glands in neck, armpit, or groin.
  • Unusual bleeding, bruising, or weakness.
If you notice these less serious side effects, talk with your doctor:
  • Dizziness or drowsiness.
  • Loss of appetite.
  • Mild pain, redness, or swelling where the shot was given.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
Review Date: 2011-02-04 Reviewed By: Keywords: ,
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