Silodosin (By mouth)

Introduction

Silodosin

Treats an enlarged prostate (also called benign prostatic hyperplasia or BPH). This medicine is an alpha-blocker.

Brand Name(s)

There may be other brand names for this medicine.

Rapaflo

When This Medicine Should Not Be Used

You should not use this medicine if you have had an allergic reaction to silodosin, or if you are also using clarithromycin (Biaxin®), itraconazole (Sporanox®), ketoconazole (Nizoral®), or ritonavir (Norvir®). Do not take this medicine if you have severe kidney disease or severe liver disease. Women and children should not use this medicine.

How to Use This Medicine

Capsule

  • Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to.
  • It is best to take this medicine with food or milk.

If a dose is missed:

  • If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine after you have finished your treatment. You will also need to throw away old medicine after the expiration date has passed.
  • Keep all medicine away from children and never share your medicine with anyone.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are using medicines for high blood pressure (such as atenolol, diltiazem, doxazosin, terazosin, verapamil, Cardura®, Hytrin®, Isoptin®, or Cardizem®). Tell your doctor if you are also using cyclosporine (such as Gengraf®, Neoral®, or Sandimmune®), erythromycin (Ery-Tab®), sildenafil (Viagra®), or tadalafil (Cialis®).

Warnings While Using This Medicine

  • Make sure your doctor knows if you have kidney disease or liver disease, or a history of prostate cancer or low blood pressure.
  • Low blood pressure (hypotension) may occur while taking this medicine. Check with your doctor right away if you have the following symptoms: blurred vision; confusion; severe dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly; sweating; or unusual tiredness or weakness.
  • This medicine may make you dizzy or lightheaded. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.
  • Before you have eye surgery for a cataract (clouding of the eye), tell the ophthalmologist (eye doctor) that you are taking this medicine.
  • Your doctor will need to check your progress at regular visits while you are using this medicine. Be sure to keep all appointments.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
  • Dark-colored urine or pale stools.
  • Lightheadedness, dizziness, or fainting when getting up from a lying or sitting position suddenly.
  • Nausea, vomiting, loss of appetite, or pain in your upper stomach.
  • Pinpoint red or purple spots on the skin.
  • Skin blisters.
  • Yellowing of your skin or the whites of your eyes.

If you notice these less serious side effects, talk with your doctor:

  • Diarrhea.
  • Headache.
  • Problems with ejaculation.
  • Sore throat.
  • Stuffy or runny nose.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Review Date: 2011-02-04 Reviewed By: Keywords: ,
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