Treats cryopyrin-associated periodic syndromes (CAPS), including familial cold autoinflammatory syndrome (FCAS) and Muckle-Wells syndrome (MWS). Also treats systemic juvenile idiopathic arthritis (SJIA).
There may be other brand names for this medicine.
When This Medicine Should Not Be Used
You should not receive this medicine if you have had an allergic reaction to canakinumab.
How to Use This Medicine
- Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin.
- A nurse or other trained health professional will give you this medicine.
- This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions. Ask your pharmacist for the Medication Guide if you do not have one.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Make sure your doctor knows if you use medicine that weakens your immune system, such as cancer medicines or steroids (such as hydrocortisone, methylprednisolone, prednisolone, prednisone). Tell your doctor if you also use a blood thinner such as warfarin (Coumadin®, Jantoven®).
- Make sure your doctor knows if you also use adalimumab (Humira®), anakinra (Kineret®), certolizumab (Cimzia®), etanercept (Enbrel®), golimumab (Simponi®), infliximab (Remicade®), or rilonacept (Arcalyst®).
- Talk to your doctor before getting flu shots or other vaccines while you are receiving this medicine. Vaccines may not work as well, or they could make you ill while you are using this medicine.
Warnings While Using This Medicine
- Make sure your doctor knows if you are pregnant or breastfeeding or if you have an immune system problem. Tell your doctor if you have an infection, HIV or AIDS, hepatitis B, hepatitis C, tuberculosis (TB) or a history of TB, or have been in close contact with someone who has active TB.
- You will need to have a skin test for tuberculosis before you start using this medicine. Tell your doctor if you or anyone in your home has ever had a positive reaction to a tuberculosis test.
- You may get infections more easily while you use this medicine. Call your doctor right away if you have symptoms of an infection, such as a fever, chills, or a cough that does not go away.
- This medicine may increase your risk of cancer. Talk to your doctor if you have concerns about this risk.
- Your doctor will need to check your progress at regular visits while you are using this medicine. Be sure to keep all appointments.
Possible Side Effects While Using This Medicine
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Fever, chills, cough, sore throat, and body aches
- Trouble swallowing
If you notice these less serious side effects, talk with your doctor:
- Dizziness or the feeling of spinning or constant movement
- Nausea or diarrhea
- Pain, itching, burning, swelling, or a lump under your skin where the shot was given
- Stuffy or runny nose