Mometasone/formoterol (By breathing)

Introduction

Formoterol Fumarate (for-MOE-ter-ol FUE-ma-rate), Mometasone Furoate (moe-MET-a-sone FURE-oh-ate)

Prevents asthma attacks. This medicine is a combination of a steroid medicine and a bronchodilator.

Brand Name(s)

There may be other brand names for this medicine.

Dulera

When This Medicine Should Not Be Used

You should not use this medicine if you have had an allergic reaction to mometasone or formoterol. You should not use this medicine if your asthma attack has already started, or if you are having a severe asthma attack.

How to Use This Medicine

Powder Under Pressure

  • Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to.
  • You will use this medicine with a device called a metered-dose inhaler. The inhaler fits on the medicine canister and turns the medicine into a fine spray that you breathe in through your mouth and to your lungs. You may be told to use a spacer, which is a tube that is placed between the inhaler and your mouth. Your caregiver will show you how to use your inhaler and the spacer (if needed).
  • Remove the cap and look at the mouthpiece to make sure it is clean.
  • When you use the inhaler for the first time, or if you have not used it for 5 days or longer, or if the inhaler has been dropped, it may not deliver the right amount of medicine with the first puff. Therefore, before using the inhaler, prime it by spraying the medicine four times into the air away from the face, and shaking it well before each spray.
  • To inhale this medicine, breathe out fully, trying to get as much air out of the lungs as possible. Put the mouthpiece just in front of your mouth with the canister upright.
  • Open your mouth and breathe in slowly and deeply (like yawning), and at the same time firmly press down on the top of the canister once.
  • Hold your breath for about 5 to 10 seconds, then breathe out slowly.
  • If you are supposed to use more than one puff, wait 1 to 2 minutes before inhaling the second puff. Repeat these steps for the next puff, starting with shaking the inhaler.
  • When you have finished all your inhalations, rinse your mouth out with water. Do not swallow the water after rinsing.
  • Clean the inhaler mouthpiece daily with warm water.
  • This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions. Ask your pharmacist for the Medication Guide if you do not have one. Your doctor might ask you to sign some forms to show that you understand this information.

If a dose is missed:

  • If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

How to Store and Dispose of This Medicine

  • Store the canister at room temperature, away from heat and direct light. Do not freeze. Do not keep this medicine inside a car where it could be exposed to extreme heat or cold. Do not poke holes in the canister or throw it into a fire, even if the canister is empty. Store the inhaler with the mouthpiece down.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of the used medicine container and any leftover medicine. You will also need to throw away old medicine after the expiration date has passed.
  • Keep all medicine away from children and never share your medicine with anyone.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • This medicine should not be used with similar inhaled medicines such as arformoterol (Brovana®), budesonide/formoterol (Symbicort®), formoterol (Foradil®, Perforomist?), or salmeterol (Serevent®).
  • Make sure your doctor knows if you are also using ketoconazole (Nizoral®), itraconazole (Sporanox®), clarithromycin (Biaxin®), telithromycin (Ketek®), theophylline (Theo-Dur®), medicine to treat HIV infection (such as atazanavir, indinavir, nelfinavir, ritonavir, saquinavir, Crixivan®, Fortovase®, Invirase®, Norvir®, or Reyataz®), or a steroid medicine (such as dexamethasone, prednisolone, prednisone, or Medrol®).
  • Make sure your doctor knows if you have used arsenic trioxide (Trisenox®), cisapride (Propulsid®), dofetilide (Tikosyn®), medicine for depression (such as amitriptyline, doxepin, nefazodone, nortriptyline, Elavil®, Pamelor®, Serzone®, or Sinequan®), certain antibiotics (such as erythromycin, levofloxacin, moxifloxacin, sparfloxacin, Avelox®, Levaquin®, or Zagam®), medicine to treat mental illness (such as haloperidol, mesoridazine, pimozide, prochlorperazine, quetiapine, thioridazine, ziprasidone, Compazine®, Geodon®, Haldol®, Mellaril®, Orap®, Serentil®, or Seroquel®), or an MAO inhibitor (such as Eldepryl®, Marplan®, Nardil®, or Parnate®) within the past 2 weeks.
  • Make sure your doctor knows if you are also using any diuretics or "water pills" (such as furosemide, hydrochlorothiazide [HCTZ], torsemide, Demadex®, or Lasix®) or blood pressure medicines (such as atenolol, metoprolol, propranolol, Inderal®, Tenormin®, or Toprol®).

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have liver disease, bone problems, heart or blood vessel disease, heart rhythm problems, high blood pressure, seizures, or low potassium in the blood. Tell your doctor if you have bone problems (such as osteoporosis), diabetes, cataracts, glaucoma, herpes simplex in your eye, thyroid problems, tuberculosis, or any type of infection.
  • This should not be the first and only medicine you use for asthma. This medicine will not stop an asthma attack that has already started. Your doctor may prescribe another medicine for you or your child to use in case of an acute asthma attack. If the other medicine does not work as well, tell your doctor right away.
  • This medicine helps prevent asthma attacks for most people, but some people may have more severe asthma attacks when they use it. Talk to your doctor about any questions or concerns you may have.
  • If any of your asthma medicines do not seem to be working as well as usual, call your doctor right away. Do not change your doses or stop using your medicines without asking your doctor.
  • If your symptoms do not improve or if they get worse, call your doctor.
  • You may get infections more easily while using this medicine. Avoid people who are sick or have infections. Tell your doctor right away if you or your child have been exposed to someone with chickenpox or measles.
  • This medicine may cause fungus infection of the mouth or throat (thrush). Tell your doctor right away if you have white patches in the mouth or throat; or pain when eating or swallowing.
  • Using too much of this medicine or using it for a long time may increase your risk of having adrenal gland problems. Talk to your doctor if you have more than one of these symptoms while you or your child are using this medicine: darkening of the skin; diarrhea; dizziness; fainting; loss of appetite; mental depression; nausea; skin rash; unusual tiredness or weakness; or vomiting.
  • If you or your child develop a skin rash, hives, or any allergic reaction to this medicine, stop using the medicine and check with your doctor as soon as possible.
  • This medicine may decrease bone mineral density when used for a long time. A low bone mineral density can cause weak bones or osteoporosis. If you have any questions about this, ask your doctor.
  • This medicine may cause children to grow more slowly than usual. Talk to your child's doctor if you have any concerns.
  • This medicine may affect blood sugar levels. If you are diabetic and notice a change in the results of your blood or urine sugar tests, check with your doctor.
  • Your doctor may want you to carry a medical identification (ID) card stating that you are using this medicine. The card will say that you or your child may need additional medicine during an emergency, a severe asthma attack or other illness, or unusual stress.
  • Your doctor will need to check your progress at regular visits while you are using this medicine. Be sure to keep all appointments. You should have regular eye exams while using this medicine.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
  • Bone or muscle pain.
  • Chest pain.
  • Dry mouth or white patches inside mouth or throat.
  • Eye pain or trouble seeing.
  • Fast, pounding, or uneven heartbeat.
  • Fever, chills, cough, runny or stuffy nose, sore throat, and body aches.
  • Pain when eating or swallowing.
  • Tremors or nervousness.
  • Worsening of breathing problems.

If you notice these less serious side effects, talk with your doctor:

  • Headache.
  • Hoarseness or voice changes.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Review Date: 2011-02-04 Reviewed By: Keywords: ,
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