Treats and prevents ulcerative colitis, an inflammatory bowel disease.
There may be other brand names for this medicine.
Apriso, Asacol, Asacol HD, Delzicol, Lialda, Pentasa
When This Medicine Should Not Be Used
Do not use this medicine if you have had an allergic reaction to mesalamine, aminosalicylates, or salicylates (such as aspirin).
How to Use This Medicine
Delayed Release Capsule, Long Acting Capsule, Tablet, Delayed Release Tablet, Coated Tablet
- Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to.
- Swallow the capsule or tablet whole. Do not open, break, crush, or chew it.
- Delayed-release capsule: Take at least 1 hour before or 2 hours after a meal.
- Delayed-release tablet: Take with food.
- While taking the extended-release form of this medicine, part of the tablet may pass into your stools. This is normal and is nothing to worry about.
- Keep taking this medicine for the full time of treatment, even if you begin to feel better after a few days. Do not miss any doses.
If a dose is missed:
- If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.
How to Store and Dispose of This Medicine
- Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
- Delayed-release capsule or tablet: Store in a tightly closed container. The medicine bottle might come with a small pouch (desiccant) inside it. Keep this pouch in the bottle to protect the medicine from moisture.
- Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
- Keep all medicine away from children and never share your medicine with anyone.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Make sure your doctor knows if you are also using azathioprine (Imuran®), mercaptopurine (Purinethol®), or an NSAID pain or arthritis medicine (such as aspirin, diclofenac, ibuprofen, naproxen, Advil®, Aleve®, Celebrex®, Voltaren®). Tell your doctor if you are also using antacids such as Amphojel®, Maalox®, Mylanta®, or Tums®.
Warnings While Using This Medicine
- Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, a history of heart disease (such as myocarditis or pericarditis), or stomach problems (such as blockage, pyloric stenosis).
- Tell your doctor if you have had an allergic reaction to sulfasalazine (Azulfidine®).
- Check with your doctor right away if you have stomach pain, bloody diarrhea, and cramps, especially if you also have fever, headache, or a rash. These may be symptoms of an acute intolerance syndrome that your doctor will need to treat.
- The Apriso? extended-release capsules contain aspartame, which may be a problem for people who have phenylketonuria (PKU). Tell your doctor if you have PKU before taking these capsules.
- Your doctor will need to check your blood or urine at regular visits while you are using this medicine. Be sure to keep all appointments.
- Carefully follow all directions if you are changing from one brand of this medicine to a different brand. Different brands have different directions because they do not all work the same way.
Possible Side Effects While Using This Medicine
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Bloody diarrhea, severe cramping, stomach pain, possibly with fever, headache, rash
- Change in how much or how often you urinate
- Chest pain, trouble breathing
- Fast, slow, or pounding heartbeat
If you notice these less serious side effects, talk with your doctor:
- Constipation, mild diarrhea
- Muscle pain
- Nausea, vomiting, bloating
- Runny or stuffy nose